Elongation factor 1 alpha1 and genes associated with Usher syndromes are downstream targets of GBX2.
Gbx2 encodes a DNA-binding transcription factor that plays pivotal roles during embryogenesis. Gain-and loss-of-function studies in several vertebrate species have demonstrated a requirement for Gbx2 in development of the anterior hindbrain, spinal cord, inner ear, heart, and neural crest cells. How...
Main Authors: | David A Roeseler, Shrikesh Sachdev, Desire M Buckley, Trupti Joshi, Doris K Wu, Dong Xu, Mark Hannink, Samuel T Waters |
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Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2012-01-01
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Series: | PLoS ONE |
Online Access: | http://europepmc.org/articles/PMC3493575?pdf=render |
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