Implementation of new parameters in 24-hour pH monitoring andimpedance

24-hour oesophageal multichannel impedance and  pH monitoring is  the  gold standard in the  diagnostic process of gastroesophageal reflux disease. Together with oesophagogastroduodenoscopy, it enables to distinguish different kinds of this disease and implement appropriate treatment. Recently, tha...

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Main Authors: Karolina Korszun, Przemysław Dyrla, Jerzy Gil
Format: Article
Language:English
Published: Medical Communications Sp. z o.o. 2016-09-01
Series:Pediatria i Medycyna Rodzinna
Subjects:
Online Access:http://www.pimr.pl/index.php/issues/2016-vol-12-no-3/implementation-of-new-parameters-in-24-hour-ph-monitoring-and-impedance?aid=970
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author Karolina Korszun
Przemysław Dyrla
Jerzy Gil
author_facet Karolina Korszun
Przemysław Dyrla
Jerzy Gil
author_sort Karolina Korszun
collection DOAJ
description 24-hour oesophageal multichannel impedance and  pH monitoring is  the  gold standard in the  diagnostic process of gastroesophageal reflux disease. Together with oesophagogastroduodenoscopy, it enables to distinguish different kinds of this disease and implement appropriate treatment. Recently, thanks to impedance, it was attempted to evaluate new parameters that could be helpful in diagnosis of gastroesophageal reflux disease and its differentiation from functional heartburn. One of these parameters is baseline impedance. It is measured when no swallows and refluxes occur in the oesophagus, i.e. when the oesophageal wall stays still. Postreflux swallow-induced peristaltic wave (PSPW) index is another parameter measured in 24-hour oesophageal multichannel intraluminal impedance and pH-monitoring. It is a quotient of the number of reflux episodes with postreflux swallow-induced peristaltic wave and the total number of reflux episodes. It was proven that baseline impedance and postreflux swallow-induced peristaltic wave index are correlated with oesophageal mucosa integrity. Values of these parameters differ in healthy volunteers, patients with functional heartburn as well as with erosive and nonerosive gastroesophageal reflux disease. They may be useful in the  diagnosis, but also in making decisions about pharmacological or surgical treatment. These parameters are not evaluated during 24-hour oesophageal multichannel impedance and pH-monitoring on a routine basis. Since the available studies have been carried out on small groups of patients, there is a need for further investigation to assess the diagnostic value of baseline impedance and PSPW.
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spelling doaj.art-7f8db5406dd6480186d2f4da91ccb5b72022-12-22T01:51:36ZengMedical Communications Sp. z o.o.Pediatria i Medycyna Rodzinna1734-15312451-07422016-09-0112425626310.15557/PiMR.2016.0026Implementation of new parameters in 24-hour pH monitoring andimpedanceKarolina Korszun0Przemysław Dyrla1Jerzy Gil2Department of Gastroenterology, Military Institute of Medicine, Warsaw, PolandDepartment of Gastroenterology, Military Institute of Medicine, Warsaw, PolandDepartment of Gastroenterology, Military Institute of Medicine, Warsaw, Poland24-hour oesophageal multichannel impedance and  pH monitoring is  the  gold standard in the  diagnostic process of gastroesophageal reflux disease. Together with oesophagogastroduodenoscopy, it enables to distinguish different kinds of this disease and implement appropriate treatment. Recently, thanks to impedance, it was attempted to evaluate new parameters that could be helpful in diagnosis of gastroesophageal reflux disease and its differentiation from functional heartburn. One of these parameters is baseline impedance. It is measured when no swallows and refluxes occur in the oesophagus, i.e. when the oesophageal wall stays still. Postreflux swallow-induced peristaltic wave (PSPW) index is another parameter measured in 24-hour oesophageal multichannel intraluminal impedance and pH-monitoring. It is a quotient of the number of reflux episodes with postreflux swallow-induced peristaltic wave and the total number of reflux episodes. It was proven that baseline impedance and postreflux swallow-induced peristaltic wave index are correlated with oesophageal mucosa integrity. Values of these parameters differ in healthy volunteers, patients with functional heartburn as well as with erosive and nonerosive gastroesophageal reflux disease. They may be useful in the  diagnosis, but also in making decisions about pharmacological or surgical treatment. These parameters are not evaluated during 24-hour oesophageal multichannel impedance and pH-monitoring on a routine basis. Since the available studies have been carried out on small groups of patients, there is a need for further investigation to assess the diagnostic value of baseline impedance and PSPW.http://www.pimr.pl/index.php/issues/2016-vol-12-no-3/implementation-of-new-parameters-in-24-hour-ph-monitoring-and-impedance?aid=970gastroesophageal reflux diseaserefluxbaseline impedancepostreflux swallow-induced peristaltic wave
spellingShingle Karolina Korszun
Przemysław Dyrla
Jerzy Gil
Implementation of new parameters in 24-hour pH monitoring andimpedance
Pediatria i Medycyna Rodzinna
gastroesophageal reflux disease
reflux
baseline impedance
postreflux swallow-induced peristaltic wave
title Implementation of new parameters in 24-hour pH monitoring andimpedance
title_full Implementation of new parameters in 24-hour pH monitoring andimpedance
title_fullStr Implementation of new parameters in 24-hour pH monitoring andimpedance
title_full_unstemmed Implementation of new parameters in 24-hour pH monitoring andimpedance
title_short Implementation of new parameters in 24-hour pH monitoring andimpedance
title_sort implementation of new parameters in 24 hour ph monitoring andimpedance
topic gastroesophageal reflux disease
reflux
baseline impedance
postreflux swallow-induced peristaltic wave
url http://www.pimr.pl/index.php/issues/2016-vol-12-no-3/implementation-of-new-parameters-in-24-hour-ph-monitoring-and-impedance?aid=970
work_keys_str_mv AT karolinakorszun implementationofnewparametersin24hourphmonitoringandimpedance
AT przemysławdyrla implementationofnewparametersin24hourphmonitoringandimpedance
AT jerzygil implementationofnewparametersin24hourphmonitoringandimpedance