A systematic methodology for epicardial and epiaortic echocardiography in swine research models
Abstract Background Perioperative echocardiography is of paramount importance during cardiac surgery. Nonetheless, in the experimental large‐animal setting, it might be challenging obtaining optimal imaging when using conventional imaging acquisition techniques, such as transthoracic and transesopha...
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| Format: | Article |
| Language: | English |
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Wiley
2024-01-01
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| Series: | Health Science Reports |
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| Online Access: | https://doi.org/10.1002/hsr2.1777 |
| _version_ | 1797331695752445952 |
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| author | Michelle C. Galbas Florian Meissner Alexander Asmussen Hendrik C. Straky Marius Schimmel Johanna Reuter Sebastian Grundmann Martin Czerny Wolfgang Bothe |
| author_facet | Michelle C. Galbas Florian Meissner Alexander Asmussen Hendrik C. Straky Marius Schimmel Johanna Reuter Sebastian Grundmann Martin Czerny Wolfgang Bothe |
| author_sort | Michelle C. Galbas |
| collection | DOAJ |
| description | Abstract Background Perioperative echocardiography is of paramount importance during cardiac surgery. Nonetheless, in the experimental large‐animal setting, it might be challenging obtaining optimal imaging when using conventional imaging acquisition techniques, such as transthoracic and transesophageal screenings. Open‐chest surgery allows epicardial echocardiographic assessment with direct contact between probe and heart, thus providing superior quality. Standard protocols regarding the use of epicardial ultrasound in swine for research purposes are lacking. Methods Epicardial echocardiography was performed in 10 female German Landrace pigs undergoing cardiac surgery. A structured and comprehensive protocol for epicardial echocardiography was elaborated including apical, ventricular long and short axis, as well as epiaortic planes. All experiments were approved by the local board for animal welfare and conducted in accordance with the German animal protection law (TierSchG) and the ARRIVE guidelines. Conclusions Systematic protocols using epicardial echocardiography may serve as an additional tool to assess cardiac dimensions and function in experimental scenarios with swine models. |
| first_indexed | 2024-03-08T07:38:11Z |
| format | Article |
| id | doaj.art-7f8fc1da319248b094e93e839c489c2f |
| institution | Directory Open Access Journal |
| issn | 2398-8835 |
| language | English |
| last_indexed | 2024-03-08T07:38:11Z |
| publishDate | 2024-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Health Science Reports |
| spelling | doaj.art-7f8fc1da319248b094e93e839c489c2f2024-02-02T18:04:59ZengWileyHealth Science Reports2398-88352024-01-0171n/an/a10.1002/hsr2.1777A systematic methodology for epicardial and epiaortic echocardiography in swine research modelsMichelle C. Galbas0Florian Meissner1Alexander Asmussen2Hendrik C. Straky3Marius Schimmel4Johanna Reuter5Sebastian Grundmann6Martin Czerny7Wolfgang Bothe8Department of Cardiovascular Surgery, Heart Center Freiburg, Faculty of Medicine University of Freiburg Freiburg GermanyDepartment of Cardiovascular Surgery, Heart Center Freiburg, Faculty of Medicine University of Freiburg Freiburg GermanyDepartment of Cardiology and Angiology I, Heart Center Freiburg, Faculty of Medicine University of Freiburg Freiburg GermanyDepartment of Cardiovascular Surgery, Heart Center Freiburg, Faculty of Medicine University of Freiburg Freiburg GermanyDepartment of Cardiovascular Surgery, Heart Center Freiburg, Faculty of Medicine University of Freiburg Freiburg GermanyDepartment of Cardiovascular Surgery, Heart Center Freiburg, Faculty of Medicine University of Freiburg Freiburg GermanyDepartment of Cardiology and Angiology I, Heart Center Freiburg, Faculty of Medicine University of Freiburg Freiburg GermanyDepartment of Cardiovascular Surgery, Heart Center Freiburg, Faculty of Medicine University of Freiburg Freiburg GermanyDepartment of Cardiovascular Surgery, Heart Center Freiburg, Faculty of Medicine University of Freiburg Freiburg GermanyAbstract Background Perioperative echocardiography is of paramount importance during cardiac surgery. Nonetheless, in the experimental large‐animal setting, it might be challenging obtaining optimal imaging when using conventional imaging acquisition techniques, such as transthoracic and transesophageal screenings. Open‐chest surgery allows epicardial echocardiographic assessment with direct contact between probe and heart, thus providing superior quality. Standard protocols regarding the use of epicardial ultrasound in swine for research purposes are lacking. Methods Epicardial echocardiography was performed in 10 female German Landrace pigs undergoing cardiac surgery. A structured and comprehensive protocol for epicardial echocardiography was elaborated including apical, ventricular long and short axis, as well as epiaortic planes. All experiments were approved by the local board for animal welfare and conducted in accordance with the German animal protection law (TierSchG) and the ARRIVE guidelines. Conclusions Systematic protocols using epicardial echocardiography may serve as an additional tool to assess cardiac dimensions and function in experimental scenarios with swine models.https://doi.org/10.1002/hsr2.1777animal modelcardiac surgeryintraoperative echocardiographyswine |
| spellingShingle | Michelle C. Galbas Florian Meissner Alexander Asmussen Hendrik C. Straky Marius Schimmel Johanna Reuter Sebastian Grundmann Martin Czerny Wolfgang Bothe A systematic methodology for epicardial and epiaortic echocardiography in swine research models Health Science Reports animal model cardiac surgery intraoperative echocardiography swine |
| title | A systematic methodology for epicardial and epiaortic echocardiography in swine research models |
| title_full | A systematic methodology for epicardial and epiaortic echocardiography in swine research models |
| title_fullStr | A systematic methodology for epicardial and epiaortic echocardiography in swine research models |
| title_full_unstemmed | A systematic methodology for epicardial and epiaortic echocardiography in swine research models |
| title_short | A systematic methodology for epicardial and epiaortic echocardiography in swine research models |
| title_sort | systematic methodology for epicardial and epiaortic echocardiography in swine research models |
| topic | animal model cardiac surgery intraoperative echocardiography swine |
| url | https://doi.org/10.1002/hsr2.1777 |
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