Nutritional Approaches to Modulate Cardiovascular Disease Risk in Systemic Lupus Erythematosus: A Literature Review
Systemic lupus erythematosus (SLE) is a chronic pathology characterized by a bimodal mortality pattern attributed to clinical disease activity and cardiovascular disease (CVD). A complex interaction between traditional CVD risk factors such as obesity, dyslipidemia, smoking, insulin resistance, meta...
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MDPI AG
2023-02-01
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| Series: | Nutrients |
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| Online Access: | https://www.mdpi.com/2072-6643/15/4/1036 |
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| author | Karen Pesqueda-Cendejas Melissa Rivera-Escoto Mónica R. Meza-Meza Bertha Campos-López Isela Parra-Rojas Margarita Montoya-Buelna Ulises De la Cruz-Mosso |
| author_facet | Karen Pesqueda-Cendejas Melissa Rivera-Escoto Mónica R. Meza-Meza Bertha Campos-López Isela Parra-Rojas Margarita Montoya-Buelna Ulises De la Cruz-Mosso |
| author_sort | Karen Pesqueda-Cendejas |
| collection | DOAJ |
| description | Systemic lupus erythematosus (SLE) is a chronic pathology characterized by a bimodal mortality pattern attributed to clinical disease activity and cardiovascular disease (CVD). A complex interaction between traditional CVD risk factors such as obesity, dyslipidemia, smoking, insulin resistance, metabolic syndrome, and hypertension, as well as the presence of non-traditional CVD risk factors such as hyperhomocysteinemia, pro-inflammatory cytokines, and C-reactive protein levels, has been suggested as a cause of the high prevalence of CVD in SLE patients. On the other hand, environmental factors, such as nutritional status, could influence the disease’s prognosis; several nutrients have immunomodulators, antioxidants, and anti-cardiometabolic risk properties which could reduce SLE severity and organ damage by decreasing the development of traditional and non-traditional CVD risk factors. Therefore, this critical literature review discusses the therapeutic potential of nutritional approaches that could modulate the development of the main comorbidities related to CVD risk in SLE patients. |
| first_indexed | 2024-03-11T08:19:01Z |
| format | Article |
| id | doaj.art-7f8ffb4454b14f539de9a988387e04e1 |
| institution | Directory Open Access Journal |
| issn | 2072-6643 |
| language | English |
| last_indexed | 2024-03-11T08:19:01Z |
| publishDate | 2023-02-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Nutrients |
| spelling | doaj.art-7f8ffb4454b14f539de9a988387e04e12023-11-16T22:32:21ZengMDPI AGNutrients2072-66432023-02-01154103610.3390/nu15041036Nutritional Approaches to Modulate Cardiovascular Disease Risk in Systemic Lupus Erythematosus: A Literature ReviewKaren Pesqueda-Cendejas0Melissa Rivera-Escoto1Mónica R. Meza-Meza2Bertha Campos-López3Isela Parra-Rojas4Margarita Montoya-Buelna5Ulises De la Cruz-Mosso6Red de Inmunonutrición y Genómica Nutricional en las Enfermedades Autoinmunes, Centro Universitario de Ciencias de la Salud, Universidad de Guadalajara, Guadalajara 44340, Jalisco, MexicoRed de Inmunonutrición y Genómica Nutricional en las Enfermedades Autoinmunes, Centro Universitario de Ciencias de la Salud, Universidad de Guadalajara, Guadalajara 44340, Jalisco, MexicoRed de Inmunonutrición y Genómica Nutricional en las Enfermedades Autoinmunes, Centro Universitario de Ciencias de la Salud, Universidad de Guadalajara, Guadalajara 44340, Jalisco, MexicoRed de Inmunonutrición y Genómica Nutricional en las Enfermedades Autoinmunes, Centro Universitario de Ciencias de la Salud, Universidad de Guadalajara, Guadalajara 44340, Jalisco, MexicoRed de Inmunonutrición y Genómica Nutricional en las Enfermedades Autoinmunes, Centro Universitario de Ciencias de la Salud, Universidad de Guadalajara, Guadalajara 44340, Jalisco, MexicoRed de Inmunonutrición y Genómica Nutricional en las Enfermedades Autoinmunes, Centro Universitario de Ciencias de la Salud, Universidad de Guadalajara, Guadalajara 44340, Jalisco, MexicoRed de Inmunonutrición y Genómica Nutricional en las Enfermedades Autoinmunes, Centro Universitario de Ciencias de la Salud, Universidad de Guadalajara, Guadalajara 44340, Jalisco, MexicoSystemic lupus erythematosus (SLE) is a chronic pathology characterized by a bimodal mortality pattern attributed to clinical disease activity and cardiovascular disease (CVD). A complex interaction between traditional CVD risk factors such as obesity, dyslipidemia, smoking, insulin resistance, metabolic syndrome, and hypertension, as well as the presence of non-traditional CVD risk factors such as hyperhomocysteinemia, pro-inflammatory cytokines, and C-reactive protein levels, has been suggested as a cause of the high prevalence of CVD in SLE patients. On the other hand, environmental factors, such as nutritional status, could influence the disease’s prognosis; several nutrients have immunomodulators, antioxidants, and anti-cardiometabolic risk properties which could reduce SLE severity and organ damage by decreasing the development of traditional and non-traditional CVD risk factors. Therefore, this critical literature review discusses the therapeutic potential of nutritional approaches that could modulate the development of the main comorbidities related to CVD risk in SLE patients.https://www.mdpi.com/2072-6643/15/4/1036systemic lupus erythematosuscardiovascular disease riskdyslipidemiahypertensionhyperhomocysteinemiaC-reactive protein |
| spellingShingle | Karen Pesqueda-Cendejas Melissa Rivera-Escoto Mónica R. Meza-Meza Bertha Campos-López Isela Parra-Rojas Margarita Montoya-Buelna Ulises De la Cruz-Mosso Nutritional Approaches to Modulate Cardiovascular Disease Risk in Systemic Lupus Erythematosus: A Literature Review Nutrients systemic lupus erythematosus cardiovascular disease risk dyslipidemia hypertension hyperhomocysteinemia C-reactive protein |
| title | Nutritional Approaches to Modulate Cardiovascular Disease Risk in Systemic Lupus Erythematosus: A Literature Review |
| title_full | Nutritional Approaches to Modulate Cardiovascular Disease Risk in Systemic Lupus Erythematosus: A Literature Review |
| title_fullStr | Nutritional Approaches to Modulate Cardiovascular Disease Risk in Systemic Lupus Erythematosus: A Literature Review |
| title_full_unstemmed | Nutritional Approaches to Modulate Cardiovascular Disease Risk in Systemic Lupus Erythematosus: A Literature Review |
| title_short | Nutritional Approaches to Modulate Cardiovascular Disease Risk in Systemic Lupus Erythematosus: A Literature Review |
| title_sort | nutritional approaches to modulate cardiovascular disease risk in systemic lupus erythematosus a literature review |
| topic | systemic lupus erythematosus cardiovascular disease risk dyslipidemia hypertension hyperhomocysteinemia C-reactive protein |
| url | https://www.mdpi.com/2072-6643/15/4/1036 |
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