Incidence and predictors of pericardial effusion following surgical closure of atrial septal defect in children: A single center experience
ObjectivesTo evaluate the incidence of pericardial effusion (PE) after surgical atrial septal defect (ASD) closure and to investigate the presence of predictive risk factors for its development.MethodsWe collected data from 203 patients followed at Bambino Gesù Children’s Hospital of Rome who underw...
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| Format: | Article |
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Frontiers Media S.A.
2022-08-01
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| Series: | Frontiers in Pediatrics |
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| Online Access: | https://www.frontiersin.org/articles/10.3389/fped.2022.882118/full |
| _version_ | 1798040333216382976 |
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| author | Martina Campisano Camilla Celani Alessio Franceschini Denise Pires Marafon Silvia Federici Gianluca Brancaccio Lorenzo Galletti Fabrizio De Benedetti Marcello Chinali Antonella Insalaco |
| author_facet | Martina Campisano Camilla Celani Alessio Franceschini Denise Pires Marafon Silvia Federici Gianluca Brancaccio Lorenzo Galletti Fabrizio De Benedetti Marcello Chinali Antonella Insalaco |
| author_sort | Martina Campisano |
| collection | DOAJ |
| description | ObjectivesTo evaluate the incidence of pericardial effusion (PE) after surgical atrial septal defect (ASD) closure and to investigate the presence of predictive risk factors for its development.MethodsWe collected data from 203 patients followed at Bambino Gesù Children’s Hospital of Rome who underwent cardiac surgery for ASD repair between January 2015 and September 2019.ResultsA total of 200/203 patients with different types of ASD were included. Patients were divided into two groups: Group 1) 38 (19%) who developed PE and Group 2) 162 (81%) without PE. No differences were noted between the two groups with regard to gender or age at the surgery. Fever in the 48 h after surgery was significantly more frequent in group 1 than in group 2 (23.7 vs. 2.5%; p < 0.0001). ECG at discharge showed significant ST-segment elevation in children who developed PE, 24.3 vs. 2.0% in those who did not (p < 0.0001). Group 1 patients were divided into two subgroups on the basis of the severity of PE, namely, 31 (81.6%) with mild and 7 (18.4%) with moderate/severe PE. Patients with moderate/severe PE had a significantly higher BMI value (median 19.1 Kg/m2) (range 15.9–23.4, p = 0.004).ConclusionThe presence of fever and ST-segment elevation after surgery predicts subsequent development of PE suggesting a closer follow-up for these categories of patients. A higher BMI appears to be associated with a higher risk of moderate/severe PE. |
| first_indexed | 2024-04-11T22:06:09Z |
| format | Article |
| id | doaj.art-7f9185e846a84ed39d07a35dcc0c35d9 |
| institution | Directory Open Access Journal |
| issn | 2296-2360 |
| language | English |
| last_indexed | 2024-04-11T22:06:09Z |
| publishDate | 2022-08-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Pediatrics |
| spelling | doaj.art-7f9185e846a84ed39d07a35dcc0c35d92022-12-22T04:00:43ZengFrontiers Media S.A.Frontiers in Pediatrics2296-23602022-08-011010.3389/fped.2022.882118882118Incidence and predictors of pericardial effusion following surgical closure of atrial septal defect in children: A single center experienceMartina Campisano0Camilla Celani1Alessio Franceschini2Denise Pires Marafon3Silvia Federici4Gianluca Brancaccio5Lorenzo Galletti6Fabrizio De Benedetti7Marcello Chinali8Antonella Insalaco9Division of Pediatric Cardiology, Bambino Gesù Children’s Hospital, Istituti di Ricovero e Cura a Carattere Scientifico (IRCCS), Rome, ItalyDivision of Rheumatology, Bambino Gesù Children’s Hospital, Istituti di Ricovero e Cura a Carattere Scientifico (IRCCS), Rome, ItalyDivision of Pediatric Cardiology, Bambino Gesù Children’s Hospital, Istituti di Ricovero e Cura a Carattere Scientifico (IRCCS), Rome, ItalyDivision of Rheumatology, Bambino Gesù Children’s Hospital, Istituti di Ricovero e Cura a Carattere Scientifico (IRCCS), Rome, ItalyDivision of Rheumatology, Bambino Gesù Children’s Hospital, Istituti di Ricovero e Cura a Carattere Scientifico (IRCCS), Rome, ItalyDivision of Pediatric Cardiology, Bambino Gesù Children’s Hospital, Istituti di Ricovero e Cura a Carattere Scientifico (IRCCS), Rome, ItalyDivision of Pediatric Cardiology, Bambino Gesù Children’s Hospital, Istituti di Ricovero e Cura a Carattere Scientifico (IRCCS), Rome, ItalyDivision of Rheumatology, Bambino Gesù Children’s Hospital, Istituti di Ricovero e Cura a Carattere Scientifico (IRCCS), Rome, ItalyDivision of Pediatric Cardiology, Bambino Gesù Children’s Hospital, Istituti di Ricovero e Cura a Carattere Scientifico (IRCCS), Rome, ItalyDivision of Rheumatology, Bambino Gesù Children’s Hospital, Istituti di Ricovero e Cura a Carattere Scientifico (IRCCS), Rome, ItalyObjectivesTo evaluate the incidence of pericardial effusion (PE) after surgical atrial septal defect (ASD) closure and to investigate the presence of predictive risk factors for its development.MethodsWe collected data from 203 patients followed at Bambino Gesù Children’s Hospital of Rome who underwent cardiac surgery for ASD repair between January 2015 and September 2019.ResultsA total of 200/203 patients with different types of ASD were included. Patients were divided into two groups: Group 1) 38 (19%) who developed PE and Group 2) 162 (81%) without PE. No differences were noted between the two groups with regard to gender or age at the surgery. Fever in the 48 h after surgery was significantly more frequent in group 1 than in group 2 (23.7 vs. 2.5%; p < 0.0001). ECG at discharge showed significant ST-segment elevation in children who developed PE, 24.3 vs. 2.0% in those who did not (p < 0.0001). Group 1 patients were divided into two subgroups on the basis of the severity of PE, namely, 31 (81.6%) with mild and 7 (18.4%) with moderate/severe PE. Patients with moderate/severe PE had a significantly higher BMI value (median 19.1 Kg/m2) (range 15.9–23.4, p = 0.004).ConclusionThe presence of fever and ST-segment elevation after surgery predicts subsequent development of PE suggesting a closer follow-up for these categories of patients. A higher BMI appears to be associated with a higher risk of moderate/severe PE.https://www.frontiersin.org/articles/10.3389/fped.2022.882118/fullatrial septal defectpericardial effusionbody mass indexpost-pericardiotomy syndromecongenital heart disease |
| spellingShingle | Martina Campisano Camilla Celani Alessio Franceschini Denise Pires Marafon Silvia Federici Gianluca Brancaccio Lorenzo Galletti Fabrizio De Benedetti Marcello Chinali Antonella Insalaco Incidence and predictors of pericardial effusion following surgical closure of atrial septal defect in children: A single center experience Frontiers in Pediatrics atrial septal defect pericardial effusion body mass index post-pericardiotomy syndrome congenital heart disease |
| title | Incidence and predictors of pericardial effusion following surgical closure of atrial septal defect in children: A single center experience |
| title_full | Incidence and predictors of pericardial effusion following surgical closure of atrial septal defect in children: A single center experience |
| title_fullStr | Incidence and predictors of pericardial effusion following surgical closure of atrial septal defect in children: A single center experience |
| title_full_unstemmed | Incidence and predictors of pericardial effusion following surgical closure of atrial septal defect in children: A single center experience |
| title_short | Incidence and predictors of pericardial effusion following surgical closure of atrial septal defect in children: A single center experience |
| title_sort | incidence and predictors of pericardial effusion following surgical closure of atrial septal defect in children a single center experience |
| topic | atrial septal defect pericardial effusion body mass index post-pericardiotomy syndrome congenital heart disease |
| url | https://www.frontiersin.org/articles/10.3389/fped.2022.882118/full |
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