B-cells expressing NgR1 and NgR3 are localized to EAE-induced inflammatory infiltrates and are stimulated by BAFF

B-cells expressing NgR1 and NgR3 are localized to EAE-induced inflammatory infiltrates and are stimulated by BAFF

Abstract We have previously reported evidence that Nogo-A activation of Nogo-receptor 1 (NgR1) can drive axonal dystrophy during the neurological progression of experimental autoimmune encephalomyelitis (EAE). However, the B-cell activating factor (BAFF/BlyS) may also be an important ligand of NgR d...

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Bibliographic Details
Main Authors: Maha M. Bakhuraysah, Paschalis Theotokis, Jae Young Lee, Amani A. Alrehaili, Pei-Mun Aui, William A. Figgett, Michael F. Azari, John-Paul Abou-Afech, Fabienne Mackay, Christopher Siatskas, Frank Alderuccio, Stephen M. Strittmatter, Nikolaos Grigoriadis, Steven Petratos
Format: Article
Language:English
Published: Nature Portfolio 2021-02-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-021-82346-6

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