Prognostic significance of the Complex "Visceral Adiposity Index" vs. simple anthropometric measures: Tehran lipid and glucose study
<p>Abstract</p> <p>Background</p> <p>Visceral adiposity index (VAI) has recently been suggested to be used as a surrogate of visceral adiposity. We examined if VAI could improve predictive performances for CVD of the Framingham's general CVD algorithm (a multivaria...
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BMC
2012-03-01
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Series: | Cardiovascular Diabetology |
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Online Access: | http://www.cardiab.com/content/11/1/20 |
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author | Mohammadreza Bozorgmanesh Farzad Hadaegh Davoud Khalili Prof Azizi |
author_facet | Mohammadreza Bozorgmanesh Farzad Hadaegh Davoud Khalili Prof Azizi |
author_sort | Mohammadreza Bozorgmanesh |
collection | DOAJ |
description | <p>Abstract</p> <p>Background</p> <p>Visceral adiposity index (VAI) has recently been suggested to be used as a surrogate of visceral adiposity. We examined if VAI could improve predictive performances for CVD of the Framingham's general CVD algorithm (a multivariate model incorporating established CVD risk factors). We compared the predictive abilities of the VAI with those of simple anthropometric measures i.e. BMI, waist-to-height ratio (WHtR) or waist-to-hip ratio (WHpR).</p> <p>Design and methods</p> <p>In a nine-year population-based follow-up, 6 407 (2 778 men) participants, free of CVD at baseline, aged ≥ 30 years were eligible for the current analysis. The risk of CVD was estimated by incorporating VAI, BMI, WHpR, and WHtR, one at a time, into multivariate accelerated failure time models.</p> <p>Results</p> <p>We documented 534 CVD events with the annual incidence rate (95%CIs) being 7.3 (6.4-8.3) among women and 13.0 (11.7-14.6) among men. Risk of future CVD increased with increasing levels of VAI among both men and women. VAI was associated with multivariate-adjusted increased risk of incident CVD among women. However, the magnitude of risk conferred by VAI was not significantly higher than those conferred by BMI, WHpR, or WHtR. Among men, after adjustment for established CVD risk factors, VAI was no longer associated with increased risk of CVD. VAI failed to add to the predictive ability of the Framingham general CVD algorithm.</p> <p>Conclusions</p> <p>Using VAI instead of simple anthropometric measures may lead to loss of much information needed for predicting incident CVD.</p> |
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format | Article |
id | doaj.art-7f9a72c49e18424da9d639a10f78d97c |
institution | Directory Open Access Journal |
issn | 1475-2840 |
language | English |
last_indexed | 2024-12-21T20:17:26Z |
publishDate | 2012-03-01 |
publisher | BMC |
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series | Cardiovascular Diabetology |
spelling | doaj.art-7f9a72c49e18424da9d639a10f78d97c2022-12-21T18:51:34ZengBMCCardiovascular Diabetology1475-28402012-03-011112010.1186/1475-2840-11-20Prognostic significance of the Complex "Visceral Adiposity Index" vs. simple anthropometric measures: Tehran lipid and glucose studyMohammadreza BozorgmaneshFarzad HadaeghDavoud KhaliliProf Azizi<p>Abstract</p> <p>Background</p> <p>Visceral adiposity index (VAI) has recently been suggested to be used as a surrogate of visceral adiposity. We examined if VAI could improve predictive performances for CVD of the Framingham's general CVD algorithm (a multivariate model incorporating established CVD risk factors). We compared the predictive abilities of the VAI with those of simple anthropometric measures i.e. BMI, waist-to-height ratio (WHtR) or waist-to-hip ratio (WHpR).</p> <p>Design and methods</p> <p>In a nine-year population-based follow-up, 6 407 (2 778 men) participants, free of CVD at baseline, aged ≥ 30 years were eligible for the current analysis. The risk of CVD was estimated by incorporating VAI, BMI, WHpR, and WHtR, one at a time, into multivariate accelerated failure time models.</p> <p>Results</p> <p>We documented 534 CVD events with the annual incidence rate (95%CIs) being 7.3 (6.4-8.3) among women and 13.0 (11.7-14.6) among men. Risk of future CVD increased with increasing levels of VAI among both men and women. VAI was associated with multivariate-adjusted increased risk of incident CVD among women. However, the magnitude of risk conferred by VAI was not significantly higher than those conferred by BMI, WHpR, or WHtR. Among men, after adjustment for established CVD risk factors, VAI was no longer associated with increased risk of CVD. VAI failed to add to the predictive ability of the Framingham general CVD algorithm.</p> <p>Conclusions</p> <p>Using VAI instead of simple anthropometric measures may lead to loss of much information needed for predicting incident CVD.</p>http://www.cardiab.com/content/11/1/20Body mass indexCardiovascular diseasePredictionVisceral adiposity indexWaist- to-height ratioWaist-to-hip ratio |
spellingShingle | Mohammadreza Bozorgmanesh Farzad Hadaegh Davoud Khalili Prof Azizi Prognostic significance of the Complex "Visceral Adiposity Index" vs. simple anthropometric measures: Tehran lipid and glucose study Cardiovascular Diabetology Body mass index Cardiovascular disease Prediction Visceral adiposity index Waist- to-height ratio Waist-to-hip ratio |
title | Prognostic significance of the Complex "Visceral Adiposity Index" vs. simple anthropometric measures: Tehran lipid and glucose study |
title_full | Prognostic significance of the Complex "Visceral Adiposity Index" vs. simple anthropometric measures: Tehran lipid and glucose study |
title_fullStr | Prognostic significance of the Complex "Visceral Adiposity Index" vs. simple anthropometric measures: Tehran lipid and glucose study |
title_full_unstemmed | Prognostic significance of the Complex "Visceral Adiposity Index" vs. simple anthropometric measures: Tehran lipid and glucose study |
title_short | Prognostic significance of the Complex "Visceral Adiposity Index" vs. simple anthropometric measures: Tehran lipid and glucose study |
title_sort | prognostic significance of the complex visceral adiposity index vs simple anthropometric measures tehran lipid and glucose study |
topic | Body mass index Cardiovascular disease Prediction Visceral adiposity index Waist- to-height ratio Waist-to-hip ratio |
url | http://www.cardiab.com/content/11/1/20 |
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