Thymoma and Thymic Carcinoma: Surgical Resection and Multidisciplinary Treatment
Thymoma and thymic carcinoma are the most common tumors of the anterior mediastinum and a relatively rare type of thoracic cancer. The prerequisite for surgery is clinical staging and operative evaluation, both of which are based on medical imaging. The best strategy for treating a thymic epithelial...
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MDPI AG
2023-03-01
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| Series: | Cancers |
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| Online Access: | https://www.mdpi.com/2072-6694/15/7/1953 |
| _version_ | 1797608253016768512 |
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| author | Yue Zhang Dong Lin Beatrice Aramini Fu Yang Xi Chen Xing Wang Liang Wu Wei Huang Jiang Fan |
| author_facet | Yue Zhang Dong Lin Beatrice Aramini Fu Yang Xi Chen Xing Wang Liang Wu Wei Huang Jiang Fan |
| author_sort | Yue Zhang |
| collection | DOAJ |
| description | Thymoma and thymic carcinoma are the most common tumors of the anterior mediastinum and a relatively rare type of thoracic cancer. The prerequisite for surgery is clinical staging and operative evaluation, both of which are based on medical imaging. The best strategy for treating a thymic epithelial tumor is surgical resection of the organ and surrounding tissue. Thymectomy modalities vary, including open surgery and minimally invasive surgery, and surgeons have used various innovations to better meet the needs of the procedure; therefore, it is critical to select the appropriate procedure based on the patient’s characteristics. Evaluation of resectability is the first step of surgical resection for thymic tumors without distant metastasis. The decision regarding unresectability should be made carefully. During subsequent chemotherapy or chemoradiotherapy, reevaluation of whether an area is resectable or not remains essential. Despite numerous technological advances in the surgical treatment of thymic tumors, several contentious issues remain, including the selection of surgical approaches for difficult cases, the selection of video-assisted thoracoscopic approaches, the evaluation of resectability, minimally invasive surgery for locally advanced thymic tumors, lymphadenectomy in thymic tumors, neoadjuvant therapy for thymic tumors, debulking surgery, and salvage surgery. In solving these problems, the surgeon’s judgment, surgical experience, and surgical skills are especially important. |
| first_indexed | 2024-03-11T05:41:58Z |
| format | Article |
| id | doaj.art-7f9d742178724c70bb7f72173630ee22 |
| institution | Directory Open Access Journal |
| issn | 2072-6694 |
| language | English |
| last_indexed | 2024-03-11T05:41:58Z |
| publishDate | 2023-03-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Cancers |
| spelling | doaj.art-7f9d742178724c70bb7f72173630ee222023-11-17T16:24:02ZengMDPI AGCancers2072-66942023-03-01157195310.3390/cancers15071953Thymoma and Thymic Carcinoma: Surgical Resection and Multidisciplinary TreatmentYue Zhang0Dong Lin1Beatrice Aramini2Fu Yang3Xi Chen4Xing Wang5Liang Wu6Wei Huang7Jiang Fan8Department of Thoracic Surgery, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai 200025, ChinaDepartment of Thoracic Surgery, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai 200025, ChinaDivision of Thoracic Surgery, Department of Medical and Surgical Sciences-DIMEC of the Alma Mater Studiorum, University of Bologna, G.B. Morgagni-L. Pierantoni Hospital, 47121 Forlì, ItalyDepartment of Thoracic Surgery, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai 200025, ChinaDepartment of Thoracic Surgery, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai 200025, ChinaDepartment of Thoracic Surgery, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai 200025, ChinaDepartment of Thoracic Surgery, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai 200025, ChinaDepartment of Thoracic Surgery, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai 200025, ChinaDepartment of Thoracic Surgery, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai 200025, ChinaThymoma and thymic carcinoma are the most common tumors of the anterior mediastinum and a relatively rare type of thoracic cancer. The prerequisite for surgery is clinical staging and operative evaluation, both of which are based on medical imaging. The best strategy for treating a thymic epithelial tumor is surgical resection of the organ and surrounding tissue. Thymectomy modalities vary, including open surgery and minimally invasive surgery, and surgeons have used various innovations to better meet the needs of the procedure; therefore, it is critical to select the appropriate procedure based on the patient’s characteristics. Evaluation of resectability is the first step of surgical resection for thymic tumors without distant metastasis. The decision regarding unresectability should be made carefully. During subsequent chemotherapy or chemoradiotherapy, reevaluation of whether an area is resectable or not remains essential. Despite numerous technological advances in the surgical treatment of thymic tumors, several contentious issues remain, including the selection of surgical approaches for difficult cases, the selection of video-assisted thoracoscopic approaches, the evaluation of resectability, minimally invasive surgery for locally advanced thymic tumors, lymphadenectomy in thymic tumors, neoadjuvant therapy for thymic tumors, debulking surgery, and salvage surgery. In solving these problems, the surgeon’s judgment, surgical experience, and surgical skills are especially important.https://www.mdpi.com/2072-6694/15/7/1953thymomathymic carcinomasurgerymultidisciplinary treatmentresectabilitysubxiphoid thymectomy |
| spellingShingle | Yue Zhang Dong Lin Beatrice Aramini Fu Yang Xi Chen Xing Wang Liang Wu Wei Huang Jiang Fan Thymoma and Thymic Carcinoma: Surgical Resection and Multidisciplinary Treatment Cancers thymoma thymic carcinoma surgery multidisciplinary treatment resectability subxiphoid thymectomy |
| title | Thymoma and Thymic Carcinoma: Surgical Resection and Multidisciplinary Treatment |
| title_full | Thymoma and Thymic Carcinoma: Surgical Resection and Multidisciplinary Treatment |
| title_fullStr | Thymoma and Thymic Carcinoma: Surgical Resection and Multidisciplinary Treatment |
| title_full_unstemmed | Thymoma and Thymic Carcinoma: Surgical Resection and Multidisciplinary Treatment |
| title_short | Thymoma and Thymic Carcinoma: Surgical Resection and Multidisciplinary Treatment |
| title_sort | thymoma and thymic carcinoma surgical resection and multidisciplinary treatment |
| topic | thymoma thymic carcinoma surgery multidisciplinary treatment resectability subxiphoid thymectomy |
| url | https://www.mdpi.com/2072-6694/15/7/1953 |
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