Sotorasib Shows Intracranial Activity in Patients with KRAS G12C-Mutated Adenocarcinoma of the Lung and Untreated Active Brain Metastases

Sotorasib Shows Intracranial Activity in Patients with KRAS G12C-Mutated Adenocarcinoma of the Lung and Untreated Active Brain Metastases

Treatment with sotorasib has shown intracranial complete responses and continued intracranial stabilization in KRAS G12C-mutated non-small-cell lung carcinoma (NSCLC) patients with previously treated, stable brain metastases in a post hoc analysis of the ongoing CodeBreaK 100 trial. We present the c...

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Bibliographic Details
Main Authors: Kira-Lee Koster, Christina Appenzeller, Arno Lauber, Martin Früh, Sabine Schmid
Format: Article
Language:English
Published: Karger Publishers 2022-08-01
Series:Case Reports in Oncology
Subjects:
kras-mutated nsclc
kras inhibition
nsclc with active brain metastases
Online Access:https://www.karger.com/Article/FullText/525341

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