Amblyomma sculptum Salivary Protease Inhibitors as Potential Anti-Tick Vaccines

Amblyomma sculptum Salivary Protease Inhibitors as Potential Anti-Tick Vaccines

Amblyomma sculptum is the main tick associated with human bites in Brazil and the main vector of Rickettsia rickettsii, the causative agent of the most severe form of Brazilian spotted fever. Molecules produced in the salivary glands are directly related to feeding success and vector competence. In...

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Bibliographic Details
Main Authors: Gabriel Cerqueira Alves Costa, Izabela Cosso Tavares Ribeiro, Otoni Melo-Junior, Nelder F. Gontijo, Mauricio R.V. Sant’Anna, Marcos H. Pereira, Grasielle C.D. Pessoa, Leonardo B. Koerich, Fabiano Oliveira, Jesus G. Valenzuela, Rodolfo Cordeiro Giunchetti, Ricardo Toshio Fujiwara, Daniella Castanheira Bartholomeu, Ricardo N. Araujo
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-02-01
Series:Frontiers in Immunology
Subjects:
Amblyomma sculptum
saliva
antihemostatic
complement inhibitors
vaccine
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2020.611104/full

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