TB SKIN TEST RESPONSE IN CHILDREN WITH HIV INFECTION
The paper presents the results of tuberculin and recombinant tuberculosis allergen (diaskintest) skin tests in HIV-infected children with tuberculosis. In general, the conducted investigations have shown that the tuberculin tests are of definite value in diagnosing tuberculosis in HIV-infected child...
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| Format: | Article |
| Language: | Russian |
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New Terra Publishing House
2014-07-01
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| Series: | Туберкулез и болезни лёгких |
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| Online Access: | https://www.tibl-journal.com/jour/article/view/102 |
| Summary: | The paper presents the results of tuberculin and recombinant tuberculosis allergen (diaskintest) skin tests in HIV-infected children with tuberculosis. In general, the conducted investigations have shown that the tuberculin tests are of definite value in diagnosing tuberculosis in HIV-infected children. However, the lower the blood CD4 lymphocyte count, the less frequently the positive skin tests were recorded: the rate of recorded positive tuberculin tests was nearly 20% in patients with CD4 counts less than 200 cells/µl and it approximated those (within 85%) in non-HIV-infected patients with CD4 counts more than 500 cells/µl. The susceptibility to the diaskintest also decreased as immunodeficiency increased and it was comparable to that of the tuberculin test. |
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| ISSN: | 2075-1230 2542-1506 |