Protective Effect and Mechanism of Melatonin on Cisplatin-Induced Ovarian Damage in Mice

Protective Effect and Mechanism of Melatonin on Cisplatin-Induced Ovarian Damage in Mice

Chemotherapeutics’ development has enhanced the survival rate of cancer patients; however, adverse effects of chemotherapeutics on ovarian functions cause fertility loss in female cancer patients. Cisplatin (CP), an important chemotherapeutic drug for treating solid tumors, has adversely affected ov...

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Bibliographic Details
Main Authors: Fen Xing, Mengyao Wang, Zhiming Ding, Junhui Zhang, Simin Ding, Lingge Shi, Qinge Xie, Muhammad Jamil Ahmad, Zhaolian Wei, Liang Tang, Dan Liang, Yunxia Cao, Yajing Liu
Format: Article
Language:English
Published: MDPI AG 2022-12-01
Series:Journal of Clinical Medicine
Subjects:
cisplatin
melatonin
ovarian damage
MAPK pathway
mitochondrial function
Online Access:https://www.mdpi.com/2077-0383/11/24/7383

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