Multicentric peripheral T-cell lymphoma, bilateral granulosa cell tumor, and papillary ovarian adenocarcinoma in a female dog - case report
ABSTRACT The frequency of ovarian neoplasms in dogs is low, and these tumors are often underdiagnosed mainly due to nonspecific clinical signs. Multiple ovarian tumors are rarely described in dogs and can be of primary or secondary origin. Lymphomas, in turn, are among the most common malignant neop...
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| Format: | Article |
| Language: | English |
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Universidade Federal de Minas Gerais
2024-02-01
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| Series: | Arquivo Brasileiro de Medicina Veterinária e Zootecnia |
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| Online Access: | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0102-09352024000200254&tlng=en |
| _version_ | 1797302348776734720 |
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| author | J.G. Wronski K.Y.R. Nakagaki E.A. Viscone M.M. Nunes G.D. Cassali |
| author_facet | J.G. Wronski K.Y.R. Nakagaki E.A. Viscone M.M. Nunes G.D. Cassali |
| author_sort | J.G. Wronski |
| collection | DOAJ |
| description | ABSTRACT The frequency of ovarian neoplasms in dogs is low, and these tumors are often underdiagnosed mainly due to nonspecific clinical signs. Multiple ovarian tumors are rarely described in dogs and can be of primary or secondary origin. Lymphomas, in turn, are among the most common malignant neoplasms in dogs, with a variable clinical course. This report describes a case of multiple concomitant ovarian tumors and a multicentric lymphoma in a dog, diagnosed histologically and confirmed by immunohistochemistry. The right and left ovaries and mesenteric lymph node of a 14-year-old mixed breed female dog were received for histopathological evaluation. Histologically, a multicentric small to intermediate cell lymphoma was diagnosed in the lymph node and both ovaries, in addition to a bilateral granulosa cell tumor and papillary adenocarcinoma in one of the ovaries. Immunohistochemistry determined the diagnosis of multicentric peripheral T-cell lymphoma. Coexisting ovarian tumors are rarely described in the literature but can occur. This is the first report of these three neoplasms occurring concomitantly in the same organ. Therefore, clinicians and pathologists should be aware of this possibility when evaluating ovaries. |
| first_indexed | 2024-03-07T23:35:32Z |
| format | Article |
| id | doaj.art-7fba62cdc9c249c4b90886eb933b0a02 |
| institution | Directory Open Access Journal |
| issn | 1678-4162 |
| language | English |
| last_indexed | 2024-03-07T23:35:32Z |
| publishDate | 2024-02-01 |
| publisher | Universidade Federal de Minas Gerais |
| record_format | Article |
| series | Arquivo Brasileiro de Medicina Veterinária e Zootecnia |
| spelling | doaj.art-7fba62cdc9c249c4b90886eb933b0a022024-02-20T07:38:34ZengUniversidade Federal de Minas GeraisArquivo Brasileiro de Medicina Veterinária e Zootecnia1678-41622024-02-0176225426010.1590/1678-4162-13130Multicentric peripheral T-cell lymphoma, bilateral granulosa cell tumor, and papillary ovarian adenocarcinoma in a female dog - case reportJ.G. Wronskihttps://orcid.org/0000-0001-5382-8037K.Y.R. Nakagakihttps://orcid.org/0000-0002-0662-9577E.A. Visconehttps://orcid.org/0000-0001-8502-3516M.M. Nuneshttps://orcid.org/0000-0003-0383-3238G.D. Cassalihttps://orcid.org/0000-0002-5650-6743ABSTRACT The frequency of ovarian neoplasms in dogs is low, and these tumors are often underdiagnosed mainly due to nonspecific clinical signs. Multiple ovarian tumors are rarely described in dogs and can be of primary or secondary origin. Lymphomas, in turn, are among the most common malignant neoplasms in dogs, with a variable clinical course. This report describes a case of multiple concomitant ovarian tumors and a multicentric lymphoma in a dog, diagnosed histologically and confirmed by immunohistochemistry. The right and left ovaries and mesenteric lymph node of a 14-year-old mixed breed female dog were received for histopathological evaluation. Histologically, a multicentric small to intermediate cell lymphoma was diagnosed in the lymph node and both ovaries, in addition to a bilateral granulosa cell tumor and papillary adenocarcinoma in one of the ovaries. Immunohistochemistry determined the diagnosis of multicentric peripheral T-cell lymphoma. Coexisting ovarian tumors are rarely described in the literature but can occur. This is the first report of these three neoplasms occurring concomitantly in the same organ. Therefore, clinicians and pathologists should be aware of this possibility when evaluating ovaries.http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0102-09352024000200254&tlng=enmultiple tumorsepithelial ovarian tumorsex cord stromal tumormulticentric lymphoma |
| spellingShingle | J.G. Wronski K.Y.R. Nakagaki E.A. Viscone M.M. Nunes G.D. Cassali Multicentric peripheral T-cell lymphoma, bilateral granulosa cell tumor, and papillary ovarian adenocarcinoma in a female dog - case report Arquivo Brasileiro de Medicina Veterinária e Zootecnia multiple tumors epithelial ovarian tumor sex cord stromal tumor multicentric lymphoma |
| title | Multicentric peripheral T-cell lymphoma, bilateral granulosa cell tumor, and papillary ovarian adenocarcinoma in a female dog - case report |
| title_full | Multicentric peripheral T-cell lymphoma, bilateral granulosa cell tumor, and papillary ovarian adenocarcinoma in a female dog - case report |
| title_fullStr | Multicentric peripheral T-cell lymphoma, bilateral granulosa cell tumor, and papillary ovarian adenocarcinoma in a female dog - case report |
| title_full_unstemmed | Multicentric peripheral T-cell lymphoma, bilateral granulosa cell tumor, and papillary ovarian adenocarcinoma in a female dog - case report |
| title_short | Multicentric peripheral T-cell lymphoma, bilateral granulosa cell tumor, and papillary ovarian adenocarcinoma in a female dog - case report |
| title_sort | multicentric peripheral t cell lymphoma bilateral granulosa cell tumor and papillary ovarian adenocarcinoma in a female dog case report |
| topic | multiple tumors epithelial ovarian tumor sex cord stromal tumor multicentric lymphoma |
| url | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0102-09352024000200254&tlng=en |
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