A progressing inflammatory pulmonary infiltrate in a patient with hyper IgE syndrome

A young man known with autosomal dominant hyper IgE syndrome and changes on his chest radiograph was presumed to be infected with Aspergillus and treated with antifungal medicine for 11 months without effect. Positron emission tomography/computed tomography imaging was suggestive of Aspergilloma but...

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Main Authors: Samal Jakobsen, Ole Hilberg, Carsten Schade Larsen, Anders Løkke
Format: Article
Language:English
Published: SAGE Publishing 2022-08-01
Series:SAGE Open Medical Case Reports
Online Access:https://doi.org/10.1177/2050313X221116674
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author Samal Jakobsen
Ole Hilberg
Carsten Schade Larsen
Anders Løkke
author_facet Samal Jakobsen
Ole Hilberg
Carsten Schade Larsen
Anders Løkke
author_sort Samal Jakobsen
collection DOAJ
description A young man known with autosomal dominant hyper IgE syndrome and changes on his chest radiograph was presumed to be infected with Aspergillus and treated with antifungal medicine for 11 months without effect. Positron emission tomography/computed tomography imaging was suggestive of Aspergilloma but bronchoalveolar lavage cultures, cytology as well as biochemistry were negative for Aspergillus. Finally, a transthoracic computed tomography-guided biopsy did not support the diagnosis of fungal infection as only chronic inflammatory changes were found. The patient was treated with Prednisolone after which the changes on his chest X-ray regressed.
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spelling doaj.art-7fbaee2c702b4cb8b6e28fc1bf7326e62022-12-22T02:49:08ZengSAGE PublishingSAGE Open Medical Case Reports2050-313X2022-08-011010.1177/2050313X221116674A progressing inflammatory pulmonary infiltrate in a patient with hyper IgE syndromeSamal Jakobsen0Ole Hilberg1Carsten Schade Larsen2Anders Løkke3Department of Pulmonology, Aarhus University Hospital, Aarhus, DenmarkDepartment of Pulmonology, Vejle Sygehus, Vejle, DenmarkDepartment of Infectious Diseases, Aarhus University Hospital, Aarhus, DenmarkDepartment of Pulmonology, Vejle Sygehus, Vejle, DenmarkA young man known with autosomal dominant hyper IgE syndrome and changes on his chest radiograph was presumed to be infected with Aspergillus and treated with antifungal medicine for 11 months without effect. Positron emission tomography/computed tomography imaging was suggestive of Aspergilloma but bronchoalveolar lavage cultures, cytology as well as biochemistry were negative for Aspergillus. Finally, a transthoracic computed tomography-guided biopsy did not support the diagnosis of fungal infection as only chronic inflammatory changes were found. The patient was treated with Prednisolone after which the changes on his chest X-ray regressed.https://doi.org/10.1177/2050313X221116674
spellingShingle Samal Jakobsen
Ole Hilberg
Carsten Schade Larsen
Anders Løkke
A progressing inflammatory pulmonary infiltrate in a patient with hyper IgE syndrome
SAGE Open Medical Case Reports
title A progressing inflammatory pulmonary infiltrate in a patient with hyper IgE syndrome
title_full A progressing inflammatory pulmonary infiltrate in a patient with hyper IgE syndrome
title_fullStr A progressing inflammatory pulmonary infiltrate in a patient with hyper IgE syndrome
title_full_unstemmed A progressing inflammatory pulmonary infiltrate in a patient with hyper IgE syndrome
title_short A progressing inflammatory pulmonary infiltrate in a patient with hyper IgE syndrome
title_sort progressing inflammatory pulmonary infiltrate in a patient with hyper ige syndrome
url https://doi.org/10.1177/2050313X221116674
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