Enzymatic Synthesis of Human Milk Fat Substitute - A Review on Technological Approaches
Human milk fat substitute (HMFS) is a structured lipid designed to resemble human milk fat. It contains 60-70% palmitic acid at the sn-2 position and unsaturated fatty acids at the sn-1,3 positions in triacylglycerol structures. HMFS is synthesized by the enzymatic interesterification of vegetable o...
| প্রধান লেখক: | , , , |
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| বিন্যাস: | প্রবন্ধ |
| ভাষা: | English |
| প্রকাশিত: |
University of Zagreb Faculty of Food Technology and Biotechnology
2021-01-01
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| মালা: | Food Technology and Biotechnology |
| বিষয়গুলি: | |
| অনলাইন ব্যবহার করুন: | https://hrcak.srce.hr/file/391948 |
| _version_ | 1827282122302291968 |
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| author | Hasrul Abdi Hasibuan Azis Boing Sitanggang Nuri Andarwulan Purwiyatno Hariyadi |
| author_facet | Hasrul Abdi Hasibuan Azis Boing Sitanggang Nuri Andarwulan Purwiyatno Hariyadi |
| author_sort | Hasrul Abdi Hasibuan |
| collection | DOAJ |
| description | Human milk fat substitute (HMFS) is a structured lipid designed to resemble human milk fat. It contains 60-70% palmitic acid at the sn-2 position and unsaturated fatty acids at the sn-1,3 positions in triacylglycerol structures. HMFS is synthesized by the enzymatic interesterification of vegetable oils, animal fats or a blend of oils. The efficiency of HMFS synthesis can be enhanced through the selection of appropriate substrates, enzymes and reaction methods. This review focuses on the synthesis of HMFS by lipase-catalyzed interesterification and provides a detailed overview of biocatalysts, substrates, synthesis methods, factors influencing the synthesis and purification process for HMFS production. Major challenges and future research in the synthesis of HMFS are also discussed. This review can be used as an information for developing future strategies in producing HMFS. |
| first_indexed | 2024-04-24T09:12:48Z |
| format | Article |
| id | doaj.art-7fbe41f18bbc4b2ab5a362382ef5a50c |
| institution | Directory Open Access Journal |
| issn | 1330-9862 1334-2606 |
| language | English |
| last_indexed | 2024-04-24T09:12:48Z |
| publishDate | 2021-01-01 |
| publisher | University of Zagreb Faculty of Food Technology and Biotechnology |
| record_format | Article |
| series | Food Technology and Biotechnology |
| spelling | doaj.art-7fbe41f18bbc4b2ab5a362382ef5a50c2024-04-15T17:28:56ZengUniversity of Zagreb Faculty of Food Technology and BiotechnologyFood Technology and Biotechnology1330-98621334-26062021-01-0159447549510.17113/ftb.59.04.21.7205Enzymatic Synthesis of Human Milk Fat Substitute - A Review on Technological ApproachesHasrul Abdi Hasibuan0Azis Boing Sitanggang1Nuri Andarwulan2Purwiyatno Hariyadi3Department of Food Science and Technology, Faculty of Agricultural Engineering and Technology, IPB University (Bogor Agricultural Universi), Campus IPB Dramaga, Raya Dramaga, 16680 Bogor, IndonesiaDepartment of Food Science and Technology, Faculty of Agricultural Engineering and Technology, IPB University (Bogor Agricultural Universi), Campus IPB Dramaga, Raya Dramaga, 16680 Bogor, IndonesiaDepartment of Food Science and Technology, Faculty of Agricultural Engineering and Technology, IPB University (Bogor Agricultural Universi), Campus IPB Dramaga, Raya Dramaga, 16680 Bogor, IndonesiaDepartment of Food Science and Technology, Faculty of Agricultural Engineering and Technology, IPB University (Bogor Agricultural Universi), Campus IPB Dramaga, Raya Dramaga, 16680 Bogor, IndonesiaHuman milk fat substitute (HMFS) is a structured lipid designed to resemble human milk fat. It contains 60-70% palmitic acid at the sn-2 position and unsaturated fatty acids at the sn-1,3 positions in triacylglycerol structures. HMFS is synthesized by the enzymatic interesterification of vegetable oils, animal fats or a blend of oils. The efficiency of HMFS synthesis can be enhanced through the selection of appropriate substrates, enzymes and reaction methods. This review focuses on the synthesis of HMFS by lipase-catalyzed interesterification and provides a detailed overview of biocatalysts, substrates, synthesis methods, factors influencing the synthesis and purification process for HMFS production. Major challenges and future research in the synthesis of HMFS are also discussed. This review can be used as an information for developing future strategies in producing HMFS.https://hrcak.srce.hr/file/391948human milk fat substituteinteresterificationlipasesn-2 palmitate |
| spellingShingle | Hasrul Abdi Hasibuan Azis Boing Sitanggang Nuri Andarwulan Purwiyatno Hariyadi Enzymatic Synthesis of Human Milk Fat Substitute - A Review on Technological Approaches Food Technology and Biotechnology human milk fat substitute interesterification lipase sn-2 palmitate |
| title | Enzymatic Synthesis of Human Milk Fat Substitute - A Review on Technological Approaches |
| title_full | Enzymatic Synthesis of Human Milk Fat Substitute - A Review on Technological Approaches |
| title_fullStr | Enzymatic Synthesis of Human Milk Fat Substitute - A Review on Technological Approaches |
| title_full_unstemmed | Enzymatic Synthesis of Human Milk Fat Substitute - A Review on Technological Approaches |
| title_short | Enzymatic Synthesis of Human Milk Fat Substitute - A Review on Technological Approaches |
| title_sort | enzymatic synthesis of human milk fat substitute a review on technological approaches |
| topic | human milk fat substitute interesterification lipase sn-2 palmitate |
| url | https://hrcak.srce.hr/file/391948 |
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