Thrombin Cleavage of Osteopontin and the Host Anti-Tumor Immune Response

Osteopontin (OPN) is a multi-functional protein that is involved in various cellular processes such as cell adhesion, migration, and signaling. There is a single conserved thrombin cleavage site in OPN that, when cleaved, yields two fragments with different properties from full-length OPN. In cancer...

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Bibliographic Details
Main Authors: Lawrence L. Leung, Timothy Myles, John Morser
Format: Article
Language:English
Published: MDPI AG 2023-07-01
Series:Cancers
Subjects:
Online Access:https://www.mdpi.com/2072-6694/15/13/3480

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