Thrombin Cleavage of Osteopontin and the Host Anti-Tumor Immune Response
Osteopontin (OPN) is a multi-functional protein that is involved in various cellular processes such as cell adhesion, migration, and signaling. There is a single conserved thrombin cleavage site in OPN that, when cleaved, yields two fragments with different properties from full-length OPN. In cancer...
Main Authors: | Lawrence L. Leung, Timothy Myles, John Morser |
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Format: | Article |
Language: | English |
Published: |
MDPI AG
2023-07-01
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Series: | Cancers |
Subjects: | |
Online Access: | https://www.mdpi.com/2072-6694/15/13/3480 |
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