AMBRA1 and its role as a target for anticancer therapy

AMBRA1 and its role as a target for anticancer therapy

The activating molecule in Beclin1-regulated autophagy protein 1 (AMBRA1) is an intrinsically disordered protein that regulates the survival and death of cancer cells by modulating autophagy. Although the roles of autophagy in cancer are controversial and context-dependent, inhibition of autophagy u...

Full description

Bibliographic Details
Main Authors: Xiang Li, Yuan Lyu, Junqi Li, Xinjun Wang
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-09-01
Series:Frontiers in Oncology
Subjects:
AMBRA1
autophagy
mitophagy
tumorigenesis
targeted therapy
Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2022.946086/full

Similar Items

Similar Items