Severe methyl bromide poisoning causing early acute renal failure and anuria: a case report

Methyl bromide is a pre-plant soil fumigant that is widely used to control nematodes, insects, and fungi in farmlands. Methyl bromide enters the human body through dermal absorption or inhalation and can damage the respiratory, nervous, circulatory, urinary, and other systems. A 62-year-old man who...

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Main Authors: Yaqian Li, Guangcai Yu, Longke Shi, Liwen Zhao, Zixin Wen, Baotian Kan, Wenjun Wang, Xiangdong Jian
Format: Article
Language:English
Published: SAGE Publishing 2022-10-01
Series:Journal of International Medical Research
Online Access:https://doi.org/10.1177/03000605221122619
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author Yaqian Li
Guangcai Yu
Longke Shi
Liwen Zhao
Zixin Wen
Baotian Kan
Wenjun Wang
Xiangdong Jian
author_facet Yaqian Li
Guangcai Yu
Longke Shi
Liwen Zhao
Zixin Wen
Baotian Kan
Wenjun Wang
Xiangdong Jian
author_sort Yaqian Li
collection DOAJ
description Methyl bromide is a pre-plant soil fumigant that is widely used to control nematodes, insects, and fungi in farmlands. Methyl bromide enters the human body through dermal absorption or inhalation and can damage the respiratory, nervous, circulatory, urinary, and other systems. A 62-year-old man who had inhaled a large amount of methyl bromide was admitted to our department. He presented with respiratory failure and pink foamy sputum. He was started on dexamethasone, alanyl glutamine, sulbactam, furosemide, vitamin B 1 , mouse nerve growth factor, and other treatments, and mechanical ventilation and continuous venovenous hemodiafiltration (CVVHF) were performed daily. He subsequently developed coagulopathy because of the CVVHF, for which protamine, recombinant human brain natriuretic peptide, and albumin were administered intravenously. Notably, the patient developed sustained anuria and eventually died owing to multiple organ failure; specifically, failure of the brain, heart, lungs, and kidneys. This report presents the diagnosis, clinical course, management, and prognosis of a patient who was treated at our hospital for severe methyl bromide poisoning.
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spelling doaj.art-7fc09eb832454fb5b2c43e845d3784342022-12-22T04:31:44ZengSAGE PublishingJournal of International Medical Research1473-23002022-10-015010.1177/03000605221122619Severe methyl bromide poisoning causing early acute renal failure and anuria: a case reportYaqian LiGuangcai YuLongke ShiLiwen ZhaoZixin WenBaotian KanWenjun WangXiangdong JianMethyl bromide is a pre-plant soil fumigant that is widely used to control nematodes, insects, and fungi in farmlands. Methyl bromide enters the human body through dermal absorption or inhalation and can damage the respiratory, nervous, circulatory, urinary, and other systems. A 62-year-old man who had inhaled a large amount of methyl bromide was admitted to our department. He presented with respiratory failure and pink foamy sputum. He was started on dexamethasone, alanyl glutamine, sulbactam, furosemide, vitamin B 1 , mouse nerve growth factor, and other treatments, and mechanical ventilation and continuous venovenous hemodiafiltration (CVVHF) were performed daily. He subsequently developed coagulopathy because of the CVVHF, for which protamine, recombinant human brain natriuretic peptide, and albumin were administered intravenously. Notably, the patient developed sustained anuria and eventually died owing to multiple organ failure; specifically, failure of the brain, heart, lungs, and kidneys. This report presents the diagnosis, clinical course, management, and prognosis of a patient who was treated at our hospital for severe methyl bromide poisoning.https://doi.org/10.1177/03000605221122619
spellingShingle Yaqian Li
Guangcai Yu
Longke Shi
Liwen Zhao
Zixin Wen
Baotian Kan
Wenjun Wang
Xiangdong Jian
Severe methyl bromide poisoning causing early acute renal failure and anuria: a case report
Journal of International Medical Research
title Severe methyl bromide poisoning causing early acute renal failure and anuria: a case report
title_full Severe methyl bromide poisoning causing early acute renal failure and anuria: a case report
title_fullStr Severe methyl bromide poisoning causing early acute renal failure and anuria: a case report
title_full_unstemmed Severe methyl bromide poisoning causing early acute renal failure and anuria: a case report
title_short Severe methyl bromide poisoning causing early acute renal failure and anuria: a case report
title_sort severe methyl bromide poisoning causing early acute renal failure and anuria a case report
url https://doi.org/10.1177/03000605221122619
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