INK128 exhibits synergy with azoles against Exophiala spp. and Fusarium spp.

INK128 exhibits synergy with azoles against Exophiala spp. and Fusarium spp.

Infections of Exophiala spp. and Fusarium spp. are often chronic and recalcitrant. Systemic disseminations, which mostly occur in immunocompromised patients, are often refractory to available antifungal therapies. The conserved target of rapamycin (TOR) orchestrates cell growth and proliferation in...

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Bibliographic Details
Main Authors: Lujuan Gao, Yi Sun, Chengyan He, Ming Li, Tongxiang Zeng, Qiaoyun Lu
Format: Article
Language:English
Published: Frontiers Media S.A. 2016-10-01
Series:Frontiers in Microbiology
Subjects:
Exophiala
Fusarium
Itraconazole
Synergy
Voriconazole
Posaconazole
Online Access:http://journal.frontiersin.org/Journal/10.3389/fmicb.2016.01658/full

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