Impacts of chitosan and its nanoformulations on the metabolic syndromes: a review
Abstract A significant public health issue worldwide is metabolic syndrome, a cluster of metabolic illnesses that comprises insulin resistance, obesity, dyslipidemia, hyperglycemia, and hypertension. The creation of natural treatments and preventions for metabolic syndrome is crucial. Chitosan, alon...
| Main Authors: | , , , , , , , , , , , |
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| Format: | Article |
| Language: | English |
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Instituto Internacional de Ecologia
2024-02-01
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| Series: | Brazilian Journal of Biology |
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| Online Access: | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1519-69842023000101081&lng=en&tlng=en |
| _version_ | 1797294008618188800 |
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| author | M. E. Abd El‐Hack M. Kamal R. S. Alazragi R. M. Alreemi A. Qadhi K. Ghafouri W. Azhar A. M. Shakoori N. Alsaffar H. M. Naffadi A. E. Taha S. A. Abdelnour |
| author_facet | M. E. Abd El‐Hack M. Kamal R. S. Alazragi R. M. Alreemi A. Qadhi K. Ghafouri W. Azhar A. M. Shakoori N. Alsaffar H. M. Naffadi A. E. Taha S. A. Abdelnour |
| author_sort | M. E. Abd El‐Hack |
| collection | DOAJ |
| description | Abstract A significant public health issue worldwide is metabolic syndrome, a cluster of metabolic illnesses that comprises insulin resistance, obesity, dyslipidemia, hyperglycemia, and hypertension. The creation of natural treatments and preventions for metabolic syndrome is crucial. Chitosan, along with its nanoformulations, is an oligomer of chitin, the second-most prevalent polymer in nature, which is created via deacetylation. Due to its plentiful biological actions in recent years, chitosan and its nanoformulations have drawn much interest. Recently, the chitosan nanoparticle-based delivery of CRISPR-Cas9 has been applied in treating metabolic syndromes. The benefits of chitosan and its nanoformulations on insulin resistance, obesity, diabetes mellitus, dyslipidemia, hyperglycemia, and hypertension will be outlined in the present review, highlighting potential mechanisms for the avoidance and medication of the metabolic syndromes by chitosan and its nanoformulations. |
| first_indexed | 2024-03-07T21:23:01Z |
| format | Article |
| id | doaj.art-7fc4103c08bd456bb7807f1d6375191c |
| institution | Directory Open Access Journal |
| issn | 1678-4375 |
| language | English |
| last_indexed | 2024-03-07T21:23:01Z |
| publishDate | 2024-02-01 |
| publisher | Instituto Internacional de Ecologia |
| record_format | Article |
| series | Brazilian Journal of Biology |
| spelling | doaj.art-7fc4103c08bd456bb7807f1d6375191c2024-02-27T07:41:17ZengInstituto Internacional de EcologiaBrazilian Journal of Biology1678-43752024-02-018310.1590/1519-6984.276530Impacts of chitosan and its nanoformulations on the metabolic syndromes: a reviewM. E. Abd El‐Hackhttps://orcid.org/0000-0002-2831-8534M. Kamalhttps://orcid.org/0000-0002-5618-7076R. S. Alazragihttps://orcid.org/0009-0002-9607-3353R. M. Alreemihttps://orcid.org/0000-0002-9062-5674A. Qadhihttps://orcid.org/0000-0001-8482-3044K. Ghafourihttps://orcid.org/0000-0001-9420-3666W. Azharhttps://orcid.org/0000-0002-9247-2149A. M. Shakoorihttps://orcid.org/0000-0002-3361-9243N. Alsaffarhttps://orcid.org/0009-0001-1525-7197H. M. Naffadihttps://orcid.org/0000-0003-4027-480XA. E. Tahahttps://orcid.org/0000-0002-0429-2587S. A. Abdelnourhttps://orcid.org/0000-0002-6873-0718Abstract A significant public health issue worldwide is metabolic syndrome, a cluster of metabolic illnesses that comprises insulin resistance, obesity, dyslipidemia, hyperglycemia, and hypertension. The creation of natural treatments and preventions for metabolic syndrome is crucial. Chitosan, along with its nanoformulations, is an oligomer of chitin, the second-most prevalent polymer in nature, which is created via deacetylation. Due to its plentiful biological actions in recent years, chitosan and its nanoformulations have drawn much interest. Recently, the chitosan nanoparticle-based delivery of CRISPR-Cas9 has been applied in treating metabolic syndromes. The benefits of chitosan and its nanoformulations on insulin resistance, obesity, diabetes mellitus, dyslipidemia, hyperglycemia, and hypertension will be outlined in the present review, highlighting potential mechanisms for the avoidance and medication of the metabolic syndromes by chitosan and its nanoformulations.http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1519-69842023000101081&lng=en&tlng=enchitosannano chitosanmetabolic syndromeobesitydiabetes |
| spellingShingle | M. E. Abd El‐Hack M. Kamal R. S. Alazragi R. M. Alreemi A. Qadhi K. Ghafouri W. Azhar A. M. Shakoori N. Alsaffar H. M. Naffadi A. E. Taha S. A. Abdelnour Impacts of chitosan and its nanoformulations on the metabolic syndromes: a review Brazilian Journal of Biology chitosan nano chitosan metabolic syndrome obesity diabetes |
| title | Impacts of chitosan and its nanoformulations on the metabolic syndromes: a review |
| title_full | Impacts of chitosan and its nanoformulations on the metabolic syndromes: a review |
| title_fullStr | Impacts of chitosan and its nanoformulations on the metabolic syndromes: a review |
| title_full_unstemmed | Impacts of chitosan and its nanoformulations on the metabolic syndromes: a review |
| title_short | Impacts of chitosan and its nanoformulations on the metabolic syndromes: a review |
| title_sort | impacts of chitosan and its nanoformulations on the metabolic syndromes a review |
| topic | chitosan nano chitosan metabolic syndrome obesity diabetes |
| url | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1519-69842023000101081&lng=en&tlng=en |
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