Unilateral Ureteral Obstruction as a Model to Investigate Fibrosis-Attenuating Treatments

Renal fibrosis is the common pathway for most forms of progressive renal disease. The Unilateral Ureteral Obstruction (UUO) model is used to cause renal fibrosis, where the primary feature of UUO is tubular injury as a result of obstructed urine flow. Furthermore, experimental UUO in rodents is beli...

Full description

Bibliographic Details
Main Authors: Elena Martínez-Klimova, Omar Emiliano Aparicio-Trejo, Edilia Tapia, José Pedraza-Chaverri
Format: Article
Language:English
Published: MDPI AG 2019-04-01
Series:Biomolecules
Subjects:
Online Access:https://www.mdpi.com/2218-273X/9/4/141