Antiviral Activity Exerted by Natural Products against Human Viruses

Viral infections are responsible for several chronic and acute diseases in both humans and animals. Despite the incredible progress in human medicine, several viral diseases, such as acquired immunodeficiency syndrome, respiratory syndromes, and hepatitis, are still associated with high morbidity an...

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Main Authors: Maria Musarra-Pizzo, Rosamaria Pennisi, Ichrak Ben-Amor, Giuseppina Mandalari, Maria Teresa Sciortino
Format: Article
Language:English
Published: MDPI AG 2021-05-01
Series:Viruses
Subjects:
Online Access:https://www.mdpi.com/1999-4915/13/5/828
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author Maria Musarra-Pizzo
Rosamaria Pennisi
Ichrak Ben-Amor
Giuseppina Mandalari
Maria Teresa Sciortino
author_facet Maria Musarra-Pizzo
Rosamaria Pennisi
Ichrak Ben-Amor
Giuseppina Mandalari
Maria Teresa Sciortino
author_sort Maria Musarra-Pizzo
collection DOAJ
description Viral infections are responsible for several chronic and acute diseases in both humans and animals. Despite the incredible progress in human medicine, several viral diseases, such as acquired immunodeficiency syndrome, respiratory syndromes, and hepatitis, are still associated with high morbidity and mortality rates in humans. Natural products from plants or other organisms are a rich source of structurally novel chemical compounds including antivirals. Indeed, in traditional medicine, many pathological conditions have been treated using plant-derived medicines. Thus, the identification of novel alternative antiviral agents is of critical importance. In this review, we summarize novel phytochemicals with antiviral activity against human viruses and their potential application in treating or preventing viral disease.
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spelling doaj.art-7fcaf42222004f138f4460d1aa3238862023-11-21T18:19:38ZengMDPI AGViruses1999-49152021-05-0113582810.3390/v13050828Antiviral Activity Exerted by Natural Products against Human VirusesMaria Musarra-Pizzo0Rosamaria Pennisi1Ichrak Ben-Amor2Giuseppina Mandalari3Maria Teresa Sciortino4Department of Chemical, Biological, Pharmaceutical and Environmental Sciences, University of Messina, Viale SS. Annunziata, 98168 Messina, ItalyDepartment of Chemical, Biological, Pharmaceutical and Environmental Sciences, University of Messina, Viale SS. Annunziata, 98168 Messina, ItalyDepartment of Chemical, Biological, Pharmaceutical and Environmental Sciences, University of Messina, Viale SS. Annunziata, 98168 Messina, ItalyDepartment of Chemical, Biological, Pharmaceutical and Environmental Sciences, University of Messina, Viale SS. Annunziata, 98168 Messina, ItalyDepartment of Chemical, Biological, Pharmaceutical and Environmental Sciences, University of Messina, Viale SS. Annunziata, 98168 Messina, ItalyViral infections are responsible for several chronic and acute diseases in both humans and animals. Despite the incredible progress in human medicine, several viral diseases, such as acquired immunodeficiency syndrome, respiratory syndromes, and hepatitis, are still associated with high morbidity and mortality rates in humans. Natural products from plants or other organisms are a rich source of structurally novel chemical compounds including antivirals. Indeed, in traditional medicine, many pathological conditions have been treated using plant-derived medicines. Thus, the identification of novel alternative antiviral agents is of critical importance. In this review, we summarize novel phytochemicals with antiviral activity against human viruses and their potential application in treating or preventing viral disease.https://www.mdpi.com/1999-4915/13/5/828viral infectionsnatural bioactive compoundsnovel antiviral drugsdrug resistance
spellingShingle Maria Musarra-Pizzo
Rosamaria Pennisi
Ichrak Ben-Amor
Giuseppina Mandalari
Maria Teresa Sciortino
Antiviral Activity Exerted by Natural Products against Human Viruses
Viruses
viral infections
natural bioactive compounds
novel antiviral drugs
drug resistance
title Antiviral Activity Exerted by Natural Products against Human Viruses
title_full Antiviral Activity Exerted by Natural Products against Human Viruses
title_fullStr Antiviral Activity Exerted by Natural Products against Human Viruses
title_full_unstemmed Antiviral Activity Exerted by Natural Products against Human Viruses
title_short Antiviral Activity Exerted by Natural Products against Human Viruses
title_sort antiviral activity exerted by natural products against human viruses
topic viral infections
natural bioactive compounds
novel antiviral drugs
drug resistance
url https://www.mdpi.com/1999-4915/13/5/828
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AT giuseppinamandalari antiviralactivityexertedbynaturalproductsagainsthumanviruses
AT mariateresasciortino antiviralactivityexertedbynaturalproductsagainsthumanviruses