Carnosine Protects Macrophages against the Toxicity of Aβ1-42 Oligomers by Decreasing Oxidative Stress

Carnosine Protects Macrophages against the Toxicity of Aβ1-42 Oligomers by Decreasing Oxidative Stress

Carnosine (β-alanyl-L-histidine) is a naturally occurring endogenous peptide widely distributed in excitable tissues such as the brain. This dipeptide has well-known antioxidant, anti-inflammatory, and anti-aggregation activities, and it may be useful for treatment of neurodegenerative disorders suc...

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Bibliographic Details
Main Authors: Giuseppe Caruso, Cristina Benatti, Nicolò Musso, Claudia G. Fresta, Annamaria Fidilio, Giorgia Spampinato, Nicoletta Brunello, Claudio Bucolo, Filippo Drago, Susan M. Lunte, Blake R. Peterson, Fabio Tascedda, Filippo Caraci
Format: Article
Language:English
Published: MDPI AG 2021-04-01
Series:Biomedicines
Subjects:
carnosine
macrophages
reactive oxygen species
nitric oxide
peroxynitrite
apoptosis
Online Access:https://www.mdpi.com/2227-9059/9/5/477

Internet

https://www.mdpi.com/2227-9059/9/5/477

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