Modern possibilities of pathogenetic therapy of patients with allergic rhinitis
The incidence of allergic rhinitis has been increasing rapidly worldwide in recent years. About 40% of the world’s population suffer from allergic inflammation of the nasal mucous membrane. Clinical manifestations of allergic rhinitis are absence or difficulty of nasal breathing, itching, sneezing,...
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| Format: | Article |
| Language: | Russian |
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Remedium Group LLC
2020-05-01
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| Series: | Медицинский совет |
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| Online Access: | https://www.med-sovet.pro/jour/article/view/5642 |
| _version_ | 1797842179145596928 |
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| author | V. M. Svistushkin G. N. Nikiforova P. S. Artamonova E. A. Shevchik |
| author_facet | V. M. Svistushkin G. N. Nikiforova P. S. Artamonova E. A. Shevchik |
| author_sort | V. M. Svistushkin |
| collection | DOAJ |
| description | The incidence of allergic rhinitis has been increasing rapidly worldwide in recent years. About 40% of the world’s population suffer from allergic inflammation of the nasal mucous membrane. Clinical manifestations of allergic rhinitis are absence or difficulty of nasal breathing, itching, sneezing, nasal congestion and rhinorrhoea, as well as swelling of the face, the presence of dermatitis in the region of the nasal wings, general malaise, smell disturbance. Manifestations of allergies by ENT organs in most cases do not pose a threat to life, but they can cause the development of other pathological processes, bad sleep, irritability, decreased efficiency, mood swings, which, in turn, adversely affects human health and reduces the quality of life. The pathogenesis of allergic rhinitis is based on an immediate hypersensitivity. According to the modern classification, depending on the nature of the course of the disease it is common to identify intermittent and persistent forms.At present, the drugs of choice in the treatment of patients with allergic rhinitis are intranasal glucocorticosteroids. However, the presence of a concomitant pathology of the nasal cavity in the patient, such as deviated septum, not only significantly impairs the course of nasal inflammatory process, but also creates obstacles to adequate delivery of topical drugs to all parts of the nasal cavity, which, in turn, reduces their effectiveness.For patients suffering from allergic rhinitis in combination with other pathology of the nasal cavity, combined oral medications may be a good alternative to intranasal sprays. Certain interest for doctors is caused by the appearance of a combined antihistamine drug on the Russian market, which includes a blocker of leukotrienes and H1-histamine receptors of the second generation – montelukast and levocetirizine. The drug can be used both in adults and children from 15 years old for treatment of intermittent and persistent forms of allergic rhinitis.Timely and properly performed therapy of allergic rhinitis allows to eliminate symptoms of the disease and prevent the development of complications. |
| first_indexed | 2024-04-09T16:43:37Z |
| format | Article |
| id | doaj.art-7fcbec7febca4f11bb43459590ed9ae5 |
| institution | Directory Open Access Journal |
| issn | 2079-701X 2658-5790 |
| language | Russian |
| last_indexed | 2024-04-09T16:43:37Z |
| publishDate | 2020-05-01 |
| publisher | Remedium Group LLC |
| record_format | Article |
| series | Медицинский совет |
| spelling | doaj.art-7fcbec7febca4f11bb43459590ed9ae52023-04-23T06:56:34ZrusRemedium Group LLCМедицинский совет2079-701X2658-57902020-05-010610110610.21518/2079-701X-2020-6-101-1065132Modern possibilities of pathogenetic therapy of patients with allergic rhinitisV. M. Svistushkin0G. N. Nikiforova1P. S. Artamonova2E. A. Shevchik3I.M. Sechenov First Moscow State Medical University (Sechenov University)I.M. Sechenov First Moscow State Medical University (Sechenov University)I.M. Sechenov First Moscow State Medical University (Sechenov University)I.M. Sechenov First Moscow State Medical University (Sechenov University)The incidence of allergic rhinitis has been increasing rapidly worldwide in recent years. About 40% of the world’s population suffer from allergic inflammation of the nasal mucous membrane. Clinical manifestations of allergic rhinitis are absence or difficulty of nasal breathing, itching, sneezing, nasal congestion and rhinorrhoea, as well as swelling of the face, the presence of dermatitis in the region of the nasal wings, general malaise, smell disturbance. Manifestations of allergies by ENT organs in most cases do not pose a threat to life, but they can cause the development of other pathological processes, bad sleep, irritability, decreased efficiency, mood swings, which, in turn, adversely affects human health and reduces the quality of life. The pathogenesis of allergic rhinitis is based on an immediate hypersensitivity. According to the modern classification, depending on the nature of the course of the disease it is common to identify intermittent and persistent forms.At present, the drugs of choice in the treatment of patients with allergic rhinitis are intranasal glucocorticosteroids. However, the presence of a concomitant pathology of the nasal cavity in the patient, such as deviated septum, not only significantly impairs the course of nasal inflammatory process, but also creates obstacles to adequate delivery of topical drugs to all parts of the nasal cavity, which, in turn, reduces their effectiveness.For patients suffering from allergic rhinitis in combination with other pathology of the nasal cavity, combined oral medications may be a good alternative to intranasal sprays. Certain interest for doctors is caused by the appearance of a combined antihistamine drug on the Russian market, which includes a blocker of leukotrienes and H1-histamine receptors of the second generation – montelukast and levocetirizine. The drug can be used both in adults and children from 15 years old for treatment of intermittent and persistent forms of allergic rhinitis.Timely and properly performed therapy of allergic rhinitis allows to eliminate symptoms of the disease and prevent the development of complications.https://www.med-sovet.pro/jour/article/view/5642allergic rhinitisnasal obstructioncurvature of the nasal septummontelukastlevocetirizine |
| spellingShingle | V. M. Svistushkin G. N. Nikiforova P. S. Artamonova E. A. Shevchik Modern possibilities of pathogenetic therapy of patients with allergic rhinitis Медицинский совет allergic rhinitis nasal obstruction curvature of the nasal septum montelukast levocetirizine |
| title | Modern possibilities of pathogenetic therapy of patients with allergic rhinitis |
| title_full | Modern possibilities of pathogenetic therapy of patients with allergic rhinitis |
| title_fullStr | Modern possibilities of pathogenetic therapy of patients with allergic rhinitis |
| title_full_unstemmed | Modern possibilities of pathogenetic therapy of patients with allergic rhinitis |
| title_short | Modern possibilities of pathogenetic therapy of patients with allergic rhinitis |
| title_sort | modern possibilities of pathogenetic therapy of patients with allergic rhinitis |
| topic | allergic rhinitis nasal obstruction curvature of the nasal septum montelukast levocetirizine |
| url | https://www.med-sovet.pro/jour/article/view/5642 |
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