Histone modification in Saccharomyces cerevisiae: A review of the current status
The budding yeast Saccharomyces cerevisiae is a well-characterized and popular model system for investigating histone modifications and the inheritance of chromatin states. The data obtained from this model organism have provided essential and critical information for understanding the complexity of...
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| Format: | Article |
| Language: | English |
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Elsevier
2023-01-01
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| Series: | Computational and Structural Biotechnology Journal |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S2001037023000843 |
| _version_ | 1827577679221620736 |
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| author | Kwon Young Chou Jun-Yeong Lee Kee-Beom Kim Eunjeong Kim Hyun-Shik Lee Hong-Yeoul Ryu |
| author_facet | Kwon Young Chou Jun-Yeong Lee Kee-Beom Kim Eunjeong Kim Hyun-Shik Lee Hong-Yeoul Ryu |
| author_sort | Kwon Young Chou |
| collection | DOAJ |
| description | The budding yeast Saccharomyces cerevisiae is a well-characterized and popular model system for investigating histone modifications and the inheritance of chromatin states. The data obtained from this model organism have provided essential and critical information for understanding the complexity of epigenetic interactions and regulation in eukaryotes. Recent advances in biotechnology have facilitated the detection and quantitation of protein post-translational modification (PTM), including acetylation, methylation, phosphorylation, ubiquitylation, sumoylation, and acylation, and led to the identification of several novel modification sites in histones. Determining the cellular function of these new histone markers is essential for understanding epigenetic mechanisms and their impact on various biological processes. In this review, we describe recent advances and current views on histone modifications and their effects on chromatin dynamics in S. cerevisiae. |
| first_indexed | 2024-03-08T21:31:20Z |
| format | Article |
| id | doaj.art-7fccd10a75414d86904ecdb2bef6039e |
| institution | Directory Open Access Journal |
| issn | 2001-0370 |
| language | English |
| last_indexed | 2024-03-08T21:31:20Z |
| publishDate | 2023-01-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Computational and Structural Biotechnology Journal |
| spelling | doaj.art-7fccd10a75414d86904ecdb2bef6039e2023-12-21T07:31:06ZengElsevierComputational and Structural Biotechnology Journal2001-03702023-01-012118431850Histone modification in Saccharomyces cerevisiae: A review of the current statusKwon Young Chou0Jun-Yeong Lee1Kee-Beom Kim2Eunjeong Kim3Hyun-Shik Lee4Hong-Yeoul Ryu5School of Life Sciences, College of National Sciences, Kyungpook National University, Daegu 41566, Republic of KoreaBK21 Plus KNU Creative BioResearch Group, School of Life Sciences, College of National Sciences, Kyungpook National University, Daegu 41566, Republic of KoreaBK21 Plus KNU Creative BioResearch Group, School of Life Sciences, College of National Sciences, Kyungpook National University, Daegu 41566, Republic of KoreaBK21 Plus KNU Creative BioResearch Group, School of Life Sciences, College of National Sciences, Kyungpook National University, Daegu 41566, Republic of KoreaBK21 Plus KNU Creative BioResearch Group, School of Life Sciences, College of National Sciences, Kyungpook National University, Daegu 41566, Republic of KoreaBK21 Plus KNU Creative BioResearch Group, School of Life Sciences, College of National Sciences, Kyungpook National University, Daegu 41566, Republic of Korea; Corresponding author.The budding yeast Saccharomyces cerevisiae is a well-characterized and popular model system for investigating histone modifications and the inheritance of chromatin states. The data obtained from this model organism have provided essential and critical information for understanding the complexity of epigenetic interactions and regulation in eukaryotes. Recent advances in biotechnology have facilitated the detection and quantitation of protein post-translational modification (PTM), including acetylation, methylation, phosphorylation, ubiquitylation, sumoylation, and acylation, and led to the identification of several novel modification sites in histones. Determining the cellular function of these new histone markers is essential for understanding epigenetic mechanisms and their impact on various biological processes. In this review, we describe recent advances and current views on histone modifications and their effects on chromatin dynamics in S. cerevisiae.http://www.sciencedirect.com/science/article/pii/S2001037023000843Histone acetylationHistone methylationHistone phosphorylationHistone ubiquitylationHistone sumoylationHistone acylation |
| spellingShingle | Kwon Young Chou Jun-Yeong Lee Kee-Beom Kim Eunjeong Kim Hyun-Shik Lee Hong-Yeoul Ryu Histone modification in Saccharomyces cerevisiae: A review of the current status Computational and Structural Biotechnology Journal Histone acetylation Histone methylation Histone phosphorylation Histone ubiquitylation Histone sumoylation Histone acylation |
| title | Histone modification in Saccharomyces cerevisiae: A review of the current status |
| title_full | Histone modification in Saccharomyces cerevisiae: A review of the current status |
| title_fullStr | Histone modification in Saccharomyces cerevisiae: A review of the current status |
| title_full_unstemmed | Histone modification in Saccharomyces cerevisiae: A review of the current status |
| title_short | Histone modification in Saccharomyces cerevisiae: A review of the current status |
| title_sort | histone modification in saccharomyces cerevisiae a review of the current status |
| topic | Histone acetylation Histone methylation Histone phosphorylation Histone ubiquitylation Histone sumoylation Histone acylation |
| url | http://www.sciencedirect.com/science/article/pii/S2001037023000843 |
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