TROMBOCYTE PARAMETRS IN NORMAL PREGNANCY AND GESTOSIS
The study of thrombocyte parameteres in healthy women in reproductive age (n=29) and pregnant women in third trimester with normal ongoing pregnancy (n=20) and with gestosis (n=38) was conducted. The relative breadth of distribution by volume(PDW, fl), share of cells with volume more than 12 fl (P-L...
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| Format: | Article |
| Language: | Russian |
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IRBIS LLC
2016-09-01
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| Series: | Акушерство, гинекология и репродукция |
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| Online Access: | https://www.gynecology.su/jour/article/view/325 |
| _version_ | 1826567159083433984 |
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| author | V. M. Pogorelov G. I. Kozinec I. O. Makarov A. V. Tochenov O. V. Rykunova |
| author_facet | V. M. Pogorelov G. I. Kozinec I. O. Makarov A. V. Tochenov O. V. Rykunova |
| author_sort | V. M. Pogorelov |
| collection | DOAJ |
| description | The study of thrombocyte parameteres in healthy women in reproductive age (n=29) and pregnant women in third trimester with normal ongoing pregnancy (n=20) and with gestosis (n=38) was conducted. The relative breadth of distribution by volume(PDW, fl), share of cells with volume more than 12 fl (P-LCR, %) and relative quantity of immature thrombocytes (IPF, %) were investigated. It was established that significant decrease of thrombocytes number takes place in pregnants compared to healthy women of reproductive age. The most significant changes were observed in women with moderate and severe gestosis. The reliable increase of relative breadth of thrombocyte distribution by volume in this group of pregnant women was also detected. This may be associated with growth of number of big and, probably, immature and functionally active thrombocytes. Thus, increase in number of immature thrombocytes, occurring in response to endothelium lesions as a part of gestosis pathogenesis, may serve as adaptation marker of thrombopoeisis system. |
| first_indexed | 2024-04-10T04:02:40Z |
| format | Article |
| id | doaj.art-7fcf737686d2454bb87603f4bd5f9f42 |
| institution | Directory Open Access Journal |
| issn | 2313-7347 2500-3194 |
| language | Russian |
| last_indexed | 2025-03-14T11:03:06Z |
| publishDate | 2016-09-01 |
| publisher | IRBIS LLC |
| record_format | Article |
| series | Акушерство, гинекология и репродукция |
| spelling | doaj.art-7fcf737686d2454bb87603f4bd5f9f422025-03-02T10:43:02ZrusIRBIS LLCАкушерство, гинекология и репродукция2313-73472500-31942016-09-01632833323TROMBOCYTE PARAMETRS IN NORMAL PREGNANCY AND GESTOSISV. M. Pogorelov0G. I. Kozinec1I. O. Makarov2A. V. Tochenov3O. V. Rykunova4FSBE Centre of Hematology, Ministry of Health and Social development, MoscowFSBE Centre of Hematology, Ministry of Health and Social development, MoscowFirst MSMU named after Sechenov I.M., MoscowFirst MSMU named after Sechenov I.M., MoscowFirst MSMU named after Sechenov I.M., MoscowThe study of thrombocyte parameteres in healthy women in reproductive age (n=29) and pregnant women in third trimester with normal ongoing pregnancy (n=20) and with gestosis (n=38) was conducted. The relative breadth of distribution by volume(PDW, fl), share of cells with volume more than 12 fl (P-LCR, %) and relative quantity of immature thrombocytes (IPF, %) were investigated. It was established that significant decrease of thrombocytes number takes place in pregnants compared to healthy women of reproductive age. The most significant changes were observed in women with moderate and severe gestosis. The reliable increase of relative breadth of thrombocyte distribution by volume in this group of pregnant women was also detected. This may be associated with growth of number of big and, probably, immature and functionally active thrombocytes. Thus, increase in number of immature thrombocytes, occurring in response to endothelium lesions as a part of gestosis pathogenesis, may serve as adaptation marker of thrombopoeisis system.https://www.gynecology.su/jour/article/view/325pregnancygestosistrombopoesisimmature platelet forms |
| spellingShingle | V. M. Pogorelov G. I. Kozinec I. O. Makarov A. V. Tochenov O. V. Rykunova TROMBOCYTE PARAMETRS IN NORMAL PREGNANCY AND GESTOSIS Акушерство, гинекология и репродукция pregnancy gestosis trombopoesis immature platelet forms |
| title | TROMBOCYTE PARAMETRS IN NORMAL PREGNANCY AND GESTOSIS |
| title_full | TROMBOCYTE PARAMETRS IN NORMAL PREGNANCY AND GESTOSIS |
| title_fullStr | TROMBOCYTE PARAMETRS IN NORMAL PREGNANCY AND GESTOSIS |
| title_full_unstemmed | TROMBOCYTE PARAMETRS IN NORMAL PREGNANCY AND GESTOSIS |
| title_short | TROMBOCYTE PARAMETRS IN NORMAL PREGNANCY AND GESTOSIS |
| title_sort | trombocyte parametrs in normal pregnancy and gestosis |
| topic | pregnancy gestosis trombopoesis immature platelet forms |
| url | https://www.gynecology.su/jour/article/view/325 |
| work_keys_str_mv | AT vmpogorelov trombocyteparametrsinnormalpregnancyandgestosis AT gikozinec trombocyteparametrsinnormalpregnancyandgestosis AT iomakarov trombocyteparametrsinnormalpregnancyandgestosis AT avtochenov trombocyteparametrsinnormalpregnancyandgestosis AT ovrykunova trombocyteparametrsinnormalpregnancyandgestosis |