MVP-Associated Filamin A Mutations Affect FlnA-PTPN12 (PTP-PEST) Interactions
Although the genetic basis of mitral valve prolapse (MVP) has now been clearly established, the molecular and cellular mechanisms involved in the pathological processes associated to a specific mutation often remain to be determined. The FLNA gene (encoding Filamin A; FlnA) was the first gene associ...
Main Authors: | Damien Duval, Pauline Labbé, Léa Bureau, Thierry Le Tourneau, Russell A. Norris, Roger R. Markwald, Robert Levine, Jean-Jacques Schott, Jean Mérot |
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Format: | Article |
Language: | English |
Published: |
MDPI AG
2015-09-01
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Series: | Journal of Cardiovascular Development and Disease |
Subjects: | |
Online Access: | http://www.mdpi.com/2308-3425/2/3/233 |
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