Novel application of anti‐human Fc nanobody for screening high‐producing CHO cells for monoclonal antibody

Novel application of anti‐human Fc nanobody for screening high‐producing CHO cells for monoclonal antibody

Abstract Animal‐derived anti‐IgG secondary antibodies are currently employed to stain and screen of human monoclonal antibody(mAb)‐producing cells, but using animal‐derived antibodies may raise the concerns of high cost, complicated operations and biological safety issues in biopharmaceutical manufa...

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Bibliographic Details
Main Authors:	Di Zhu, Zheng Wang, Yunxia Xu, Jing Lin, Mei Qiu, Jianghai Liu, Xinlei Li
Format:	Article
Language:	English
Published:	Wiley-VCH 2022-10-01
Series:	Engineering in Life Sciences
Subjects:	Chinese hamster ovary cell GFP monoclonal antibody nanobody phage display
Online Access:	https://doi.org/10.1002/elsc.202200028

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