Generation of megakaryocytic progenitors from human embryonic stem cells in a feeder- and serum-free medium.

Generation of megakaryocytic progenitors from human embryonic stem cells in a feeder- and serum-free medium.

BACKGROUND: The production of human platelets from embryonic stem cells in a defined culture system is a prerequisite for the generation of platelets for therapeutic use. As an important step towards this goal, we report the differentiation of human embryonic stem cells (hESCs) towards the megakaryo...

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Bibliographic Details
Main Authors:	Marjorie Pick, Lisa Azzola, Elissa Osborne, Edouard G Stanley, Andrew G Elefanty
Format:	Article
Language:	English
Published:	Public Library of Science (PLoS) 2013-01-01
Series:	PLoS ONE
Online Access:	http://europepmc.org/articles/PMC3570533?pdf=render

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