Supported Metal Catalysts for the Synthesis of <i>N</i>-Heterocycles
Nitrogen-containing heterocycles are important scaffolds for a large number of compounds with biological, pharmaceutical, industrial and optoelectronic applications. A wide range of different methodologies for the preparation of <i>N</i>-heterocycles are based on metal-catalyzed cyclizat...
| Main Authors: | , |
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| Format: | Article |
| Language: | English |
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MDPI AG
2022-01-01
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| Series: | Catalysts |
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| Online Access: | https://www.mdpi.com/2073-4344/12/1/68 |
| _version_ | 1797495260374368256 |
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| author | Laura Antonella Aronica Gianluigi Albano |
| author_facet | Laura Antonella Aronica Gianluigi Albano |
| author_sort | Laura Antonella Aronica |
| collection | DOAJ |
| description | Nitrogen-containing heterocycles are important scaffolds for a large number of compounds with biological, pharmaceutical, industrial and optoelectronic applications. A wide range of different methodologies for the preparation of <i>N</i>-heterocycles are based on metal-catalyzed cyclization of suitable substrates. Due to the growing interest in Green Chemistry criteria over the past two decades, the use of supported metal catalysts in the preparation of <i>N</i>-heterocycles has become a central topic in Organic Chemistry. Here we will give a critical overview of all the solid supported metal catalysts applied in the synthesis of <i>N</i>-heterocycles, following a systematic approach as a function of the type of support: (i) metal catalysts supported on inorganic matrices; (ii) metal catalysts supported on organic matrices; (iii) metal catalysts supported on hybrid inorganic-organic matrices. In particular, we will try to emphasize the effective heterogeneity and recyclability of the described metal catalysts, specifying which studies were carried out in order to evaluate these aspects. |
| first_indexed | 2024-03-10T01:45:18Z |
| format | Article |
| id | doaj.art-7fd7327b4bc14423bbe190d9e9587444 |
| institution | Directory Open Access Journal |
| issn | 2073-4344 |
| language | English |
| last_indexed | 2024-03-10T01:45:18Z |
| publishDate | 2022-01-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Catalysts |
| spelling | doaj.art-7fd7327b4bc14423bbe190d9e95874442023-11-23T13:16:35ZengMDPI AGCatalysts2073-43442022-01-011216810.3390/catal12010068Supported Metal Catalysts for the Synthesis of <i>N</i>-HeterocyclesLaura Antonella Aronica0Gianluigi Albano1Dipartimento di Chimica e Chimica Industriale, Università di Pisa, Via Giuseppe Moruzzi 13, 56124 Pisa, ItalyDipartimento di Chimica, Università degli Studi di Bari “Aldo Moro”, Via Edoardo Orabona 4, 70126 Bari, ItalyNitrogen-containing heterocycles are important scaffolds for a large number of compounds with biological, pharmaceutical, industrial and optoelectronic applications. A wide range of different methodologies for the preparation of <i>N</i>-heterocycles are based on metal-catalyzed cyclization of suitable substrates. Due to the growing interest in Green Chemistry criteria over the past two decades, the use of supported metal catalysts in the preparation of <i>N</i>-heterocycles has become a central topic in Organic Chemistry. Here we will give a critical overview of all the solid supported metal catalysts applied in the synthesis of <i>N</i>-heterocycles, following a systematic approach as a function of the type of support: (i) metal catalysts supported on inorganic matrices; (ii) metal catalysts supported on organic matrices; (iii) metal catalysts supported on hybrid inorganic-organic matrices. In particular, we will try to emphasize the effective heterogeneity and recyclability of the described metal catalysts, specifying which studies were carried out in order to evaluate these aspects.https://www.mdpi.com/2073-4344/12/1/68cyclizationsheterocyclesmetal catalystsnitrogen heterocyclessupported catalysts |
| spellingShingle | Laura Antonella Aronica Gianluigi Albano Supported Metal Catalysts for the Synthesis of <i>N</i>-Heterocycles Catalysts cyclizations heterocycles metal catalysts nitrogen heterocycles supported catalysts |
| title | Supported Metal Catalysts for the Synthesis of <i>N</i>-Heterocycles |
| title_full | Supported Metal Catalysts for the Synthesis of <i>N</i>-Heterocycles |
| title_fullStr | Supported Metal Catalysts for the Synthesis of <i>N</i>-Heterocycles |
| title_full_unstemmed | Supported Metal Catalysts for the Synthesis of <i>N</i>-Heterocycles |
| title_short | Supported Metal Catalysts for the Synthesis of <i>N</i>-Heterocycles |
| title_sort | supported metal catalysts for the synthesis of i n i heterocycles |
| topic | cyclizations heterocycles metal catalysts nitrogen heterocycles supported catalysts |
| url | https://www.mdpi.com/2073-4344/12/1/68 |
| work_keys_str_mv | AT lauraantonellaaronica supportedmetalcatalystsforthesynthesisofiniheterocycles AT gianluigialbano supportedmetalcatalystsforthesynthesisofiniheterocycles |