Non-targeted metabolomics and scavenging activity of reactive oxygen species reveal the potential of Salicornia brachiata as a functional food
Non-targeted metabolomics implied that Salicornia brachiata contains essential and sulphur-rich amino acids, which are recommended by the FAO. Total phenolic content of the plant extract contains reducing capacity and reactive oxygen species (ROS) scavenging activity. A high content of nutritive ind...
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| Format: | Article |
| Language: | English |
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Elsevier
2015-03-01
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| Series: | Journal of Functional Foods |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S175646461400406X |
| _version_ | 1818647966362107904 |
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| author | Avinash Mishra Manish Kumar Patel Bhavanath Jha |
| author_facet | Avinash Mishra Manish Kumar Patel Bhavanath Jha |
| author_sort | Avinash Mishra |
| collection | DOAJ |
| description | Non-targeted metabolomics implied that Salicornia brachiata contains essential and sulphur-rich amino acids, which are recommended by the FAO. Total phenolic content of the plant extract contains reducing capacity and reactive oxygen species (ROS) scavenging activity. A high content of nutritive indicator polyunsaturated fatty acids (PUFAs; 55–64%), including linoleic acid (C18:2; 22–27%) and alpha-linolenic acid (C18:3; 29–41%), was detected under both control and stress conditions. About 38% of saturated fatty acids, including 26% palmitic acid (C16:0), was found under the control conditions, which varied under stress. About 19 different metabolites with different bioactivities have, so far, been identified. Metabolites benzyl sulphate (m/z 93.04) and flavonoid myricatin (m/z 183.14 and 532.98) are known for their aroma and nutritive supplements. Bioactive metabolites of pharmaceutical importance, such as oxomefruside (m/z 131.07; to be used in hypertension), clonidine (m/z 210.19; to treat high blood pressure, anxiety and certain pain), carmustine (m/z 212.19; anti-neoplastic in nature) and gangliosides (m/z 879.48; anti-inflammatory), were detected in the plant extract. An important dietary supplement selenocystathionine (m/z 269.09) was identified, which is used in hyper-accumulation of anti-cancer agent selenium. Moreover, metabolites with antimicrobial (sodium cefazolin; m/z 459.82), insecticidal or fungicidal activities (dichlorophene, m/z 267.10; oxydisulfoton, m/z 271.10; sulfotep, m/z 303.41 and azothoate, m/z 355.48) were also detected. Non-targeted metabolomics, antioxidants and scavenging activities revealed the nutritional potential of the plant, making it a promising functional food for dietary supplements. |
| first_indexed | 2024-12-17T01:10:56Z |
| format | Article |
| id | doaj.art-7fd85633d6254b02862a14c07c78c646 |
| institution | Directory Open Access Journal |
| issn | 1756-4646 |
| language | English |
| last_indexed | 2024-12-17T01:10:56Z |
| publishDate | 2015-03-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Journal of Functional Foods |
| spelling | doaj.art-7fd85633d6254b02862a14c07c78c6462022-12-21T22:09:08ZengElsevierJournal of Functional Foods1756-46462015-03-01132131Non-targeted metabolomics and scavenging activity of reactive oxygen species reveal the potential of Salicornia brachiata as a functional foodAvinash Mishra0Manish Kumar Patel1Bhavanath Jha2Corresponding author. Discipline of Marine Biotechnology and Ecology, CSIR-Central Salt and Marine Chemicals Research Institute, G. B. Marg, Bhavnagar, Gujarat 364002, India. Tel.: +91 278 2567760 Ext. 6260; fax: +91 278 2567562.; Discipline of Marine Biotechnology and Ecology, CSIR-Central Salt and Marine Chemicals Research Institute, G. B. Marg, Bhavnagar, Gujarat 364002, IndiaDiscipline of Marine Biotechnology and Ecology, CSIR-Central Salt and Marine Chemicals Research Institute, G. B. Marg, Bhavnagar, Gujarat 364002, IndiaCorresponding author. Discipline of Marine Biotechnology and Ecology, CSIR-Central Salt and Marine Chemicals Research Institute, G. B. Marg, Bhavnagar, Gujarat 364002, India. Tel.: +91 278 2567352; fax: +91 278 2567562.; Discipline of Marine Biotechnology and Ecology, CSIR-Central Salt and Marine Chemicals Research Institute, G. B. Marg, Bhavnagar, Gujarat 364002, IndiaNon-targeted metabolomics implied that Salicornia brachiata contains essential and sulphur-rich amino acids, which are recommended by the FAO. Total phenolic content of the plant extract contains reducing capacity and reactive oxygen species (ROS) scavenging activity. A high content of nutritive indicator polyunsaturated fatty acids (PUFAs; 55–64%), including linoleic acid (C18:2; 22–27%) and alpha-linolenic acid (C18:3; 29–41%), was detected under both control and stress conditions. About 38% of saturated fatty acids, including 26% palmitic acid (C16:0), was found under the control conditions, which varied under stress. About 19 different metabolites with different bioactivities have, so far, been identified. Metabolites benzyl sulphate (m/z 93.04) and flavonoid myricatin (m/z 183.14 and 532.98) are known for their aroma and nutritive supplements. Bioactive metabolites of pharmaceutical importance, such as oxomefruside (m/z 131.07; to be used in hypertension), clonidine (m/z 210.19; to treat high blood pressure, anxiety and certain pain), carmustine (m/z 212.19; anti-neoplastic in nature) and gangliosides (m/z 879.48; anti-inflammatory), were detected in the plant extract. An important dietary supplement selenocystathionine (m/z 269.09) was identified, which is used in hyper-accumulation of anti-cancer agent selenium. Moreover, metabolites with antimicrobial (sodium cefazolin; m/z 459.82), insecticidal or fungicidal activities (dichlorophene, m/z 267.10; oxydisulfoton, m/z 271.10; sulfotep, m/z 303.41 and azothoate, m/z 355.48) were also detected. Non-targeted metabolomics, antioxidants and scavenging activities revealed the nutritional potential of the plant, making it a promising functional food for dietary supplements.http://www.sciencedirect.com/science/article/pii/S175646461400406XAntioxidantsBioactivityFatty acidsFunctional foodMetabolites |
| spellingShingle | Avinash Mishra Manish Kumar Patel Bhavanath Jha Non-targeted metabolomics and scavenging activity of reactive oxygen species reveal the potential of Salicornia brachiata as a functional food Journal of Functional Foods Antioxidants Bioactivity Fatty acids Functional food Metabolites |
| title | Non-targeted metabolomics and scavenging activity of reactive oxygen species reveal the potential of Salicornia brachiata as a functional food |
| title_full | Non-targeted metabolomics and scavenging activity of reactive oxygen species reveal the potential of Salicornia brachiata as a functional food |
| title_fullStr | Non-targeted metabolomics and scavenging activity of reactive oxygen species reveal the potential of Salicornia brachiata as a functional food |
| title_full_unstemmed | Non-targeted metabolomics and scavenging activity of reactive oxygen species reveal the potential of Salicornia brachiata as a functional food |
| title_short | Non-targeted metabolomics and scavenging activity of reactive oxygen species reveal the potential of Salicornia brachiata as a functional food |
| title_sort | non targeted metabolomics and scavenging activity of reactive oxygen species reveal the potential of salicornia brachiata as a functional food |
| topic | Antioxidants Bioactivity Fatty acids Functional food Metabolites |
| url | http://www.sciencedirect.com/science/article/pii/S175646461400406X |
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