Adherence to Antiretroviral Treatment for Prevention of Mother-to-Child Transmission of HIV in Eastern Ethiopia: A Cross-Sectional Study
Anwar Fedlu,1 Birhanu Alie,1 Ammas Siraj Mohammed,2 Fuad Adem,2 Abduselam Hassen1 1School of Public Health, College of Health and Medical Sciences, Haramaya University, Harar, Ethiopia; 2Department of Clinical Pharmacy, School of Pharmacy, College of Health and Medical Sciences, Haramaya University,...
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| Format: | Article |
| Language: | English |
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Dove Medical Press
2020-11-01
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| Series: | HIV/AIDS: Research and Palliative Care |
| Subjects: | |
| Online Access: | https://www.dovepress.com/adherence-to-antiretroviral-treatment-for-prevention-of-mother-to-chil-peer-reviewed-article-HIV |
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| author | Fedlu A Alie B Siraj Mohammed A Adem F Hassen A |
| author_facet | Fedlu A Alie B Siraj Mohammed A Adem F Hassen A |
| author_sort | Fedlu A |
| collection | DOAJ |
| description | Anwar Fedlu,1 Birhanu Alie,1 Ammas Siraj Mohammed,2 Fuad Adem,2 Abduselam Hassen1 1School of Public Health, College of Health and Medical Sciences, Haramaya University, Harar, Ethiopia; 2Department of Clinical Pharmacy, School of Pharmacy, College of Health and Medical Sciences, Haramaya University, Harar, EthiopiaCorrespondence: Ammas Siraj MohammedDepartment of Clinical Pharmacy, School of Pharmacy, College of Health and Medical Sciences, Haramaya University, Harar, EthiopiaEmail ammassiraj2337@gmail.comIntroduction: Even though PMTCT (prevention of mother-to-child transmission) is the most effective option to prevent vertical transmission of HIV, achieving optimal adherence has been a universal challenge to PMTCT, including Ethiopia.Objective: To assess levels of adherence and associated factors among pregnant and lactating mothers on PMTCT at public health facilities in Harar town, Harari region, Eastern Ethiopia.Methods: A facility-based cross-sectional study was conducted from April 01 to April 30, 2019, at the selected public health facilities of Harar town, Harari regional state, Eastern Ethiopia. Adherence was measured using a multi-method tool that includes pill counting and self-reporting method. Binary logistic regression analysis was used to determine factors associated with PMTCT adherence. The results were adjusted for possible confounding variables and P-value < 0.05 or CI not including 1 was considered statistically significant.Results: Of the 190 included patients, 83.2% of them had good adherence to PMTCT. Forgetfulness (79%) and being busy (71%) were among the main reasons for non-adherence to PMTCT. In multivariate logistic regression, participants who have received counseling on side effects were 3.4 times more likely to have good adherence [AOR=3.4, 95% CI: 2.1– 9.2]; those with previously known HIV status were 2.1 times more likely to have good adherence to PMTCT [AOR=2.1, 95% CI: 1.6– 7.1] and women who were knowledgeable on PMTCT were 5.2 times more likely to have good adherence [AOR=5.2, 95% CI: 1.6– 6.28].Conclusion: In this study, the overall level of adherence to PMTCT care and support was 83.2%. Counseling on side effects, knowledge about PMTCT, and pregnancy status during initiation of ART were the factors that determine adherence of pregnant and lactating women towards PMTCT service. Thus, it is recommended to raise awareness about PMTCT among all reproductive-age women by stressing the benefit of the early initiation of ART and by providing information on the possible side effect of the drugs.Keywords: pregnant and lactating women, medication adherence, PMTCT, Harar, Ethiopia |
| first_indexed | 2024-12-14T15:57:21Z |
| format | Article |
| id | doaj.art-7fd872b975734e91bb7fef81dde3d818 |
| institution | Directory Open Access Journal |
| issn | 1179-1373 |
| language | English |
| last_indexed | 2024-12-14T15:57:21Z |
| publishDate | 2020-11-01 |
| publisher | Dove Medical Press |
| record_format | Article |
| series | HIV/AIDS: Research and Palliative Care |
| spelling | doaj.art-7fd872b975734e91bb7fef81dde3d8182022-12-21T22:55:15ZengDove Medical PressHIV/AIDS: Research and Palliative Care1179-13732020-11-01Volume 1272573359150Adherence to Antiretroviral Treatment for Prevention of Mother-to-Child Transmission of HIV in Eastern Ethiopia: A Cross-Sectional StudyFedlu AAlie BSiraj Mohammed AAdem FHassen AAnwar Fedlu,1 Birhanu Alie,1 Ammas Siraj Mohammed,2 Fuad Adem,2 Abduselam Hassen1 1School of Public Health, College of Health and Medical Sciences, Haramaya University, Harar, Ethiopia; 2Department of Clinical Pharmacy, School of Pharmacy, College of Health and Medical Sciences, Haramaya University, Harar, EthiopiaCorrespondence: Ammas Siraj MohammedDepartment of Clinical Pharmacy, School of Pharmacy, College of Health and Medical Sciences, Haramaya University, Harar, EthiopiaEmail ammassiraj2337@gmail.comIntroduction: Even though PMTCT (prevention of mother-to-child transmission) is the most effective option to prevent vertical transmission of HIV, achieving optimal adherence has been a universal challenge to PMTCT, including Ethiopia.Objective: To assess levels of adherence and associated factors among pregnant and lactating mothers on PMTCT at public health facilities in Harar town, Harari region, Eastern Ethiopia.Methods: A facility-based cross-sectional study was conducted from April 01 to April 30, 2019, at the selected public health facilities of Harar town, Harari regional state, Eastern Ethiopia. Adherence was measured using a multi-method tool that includes pill counting and self-reporting method. Binary logistic regression analysis was used to determine factors associated with PMTCT adherence. The results were adjusted for possible confounding variables and P-value < 0.05 or CI not including 1 was considered statistically significant.Results: Of the 190 included patients, 83.2% of them had good adherence to PMTCT. Forgetfulness (79%) and being busy (71%) were among the main reasons for non-adherence to PMTCT. In multivariate logistic regression, participants who have received counseling on side effects were 3.4 times more likely to have good adherence [AOR=3.4, 95% CI: 2.1– 9.2]; those with previously known HIV status were 2.1 times more likely to have good adherence to PMTCT [AOR=2.1, 95% CI: 1.6– 7.1] and women who were knowledgeable on PMTCT were 5.2 times more likely to have good adherence [AOR=5.2, 95% CI: 1.6– 6.28].Conclusion: In this study, the overall level of adherence to PMTCT care and support was 83.2%. Counseling on side effects, knowledge about PMTCT, and pregnancy status during initiation of ART were the factors that determine adherence of pregnant and lactating women towards PMTCT service. Thus, it is recommended to raise awareness about PMTCT among all reproductive-age women by stressing the benefit of the early initiation of ART and by providing information on the possible side effect of the drugs.Keywords: pregnant and lactating women, medication adherence, PMTCT, Harar, Ethiopiahttps://www.dovepress.com/adherence-to-antiretroviral-treatment-for-prevention-of-mother-to-chil-peer-reviewed-article-HIVpregnant and lactating womenmedication adherencepmtcthararethiopia |
| spellingShingle | Fedlu A Alie B Siraj Mohammed A Adem F Hassen A Adherence to Antiretroviral Treatment for Prevention of Mother-to-Child Transmission of HIV in Eastern Ethiopia: A Cross-Sectional Study HIV/AIDS: Research and Palliative Care pregnant and lactating women medication adherence pmtct harar ethiopia |
| title | Adherence to Antiretroviral Treatment for Prevention of Mother-to-Child Transmission of HIV in Eastern Ethiopia: A Cross-Sectional Study |
| title_full | Adherence to Antiretroviral Treatment for Prevention of Mother-to-Child Transmission of HIV in Eastern Ethiopia: A Cross-Sectional Study |
| title_fullStr | Adherence to Antiretroviral Treatment for Prevention of Mother-to-Child Transmission of HIV in Eastern Ethiopia: A Cross-Sectional Study |
| title_full_unstemmed | Adherence to Antiretroviral Treatment for Prevention of Mother-to-Child Transmission of HIV in Eastern Ethiopia: A Cross-Sectional Study |
| title_short | Adherence to Antiretroviral Treatment for Prevention of Mother-to-Child Transmission of HIV in Eastern Ethiopia: A Cross-Sectional Study |
| title_sort | adherence to antiretroviral treatment for prevention of mother to child transmission of hiv in eastern ethiopia a cross sectional study |
| topic | pregnant and lactating women medication adherence pmtct harar ethiopia |
| url | https://www.dovepress.com/adherence-to-antiretroviral-treatment-for-prevention-of-mother-to-chil-peer-reviewed-article-HIV |
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