Strain-Specific Contribution of Eukaryotic Elongation Factor 1 Gamma to the Translation of Influenza A Virus Proteins

Strain-Specific Contribution of Eukaryotic Elongation Factor 1 Gamma to the Translation of Influenza A Virus Proteins

Influenza A virus exploits multiple host proteins during infection. To define the virus–host interactome, our group conducted a proteomics-based screen and identified 299 genes that contributed to virus replication and 24 genes that were antiviral. Of these genes, we focused on the role during virus...

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Bibliographic Details
Main Authors: Shuhei Sammaibashi, Seiya Yamayoshi, Yoshihiro Kawaoka
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-06-01
Series:Frontiers in Microbiology
Subjects:
influenza virus
host protein
eEF1G
protein translation
PB2
PA
Online Access:https://www.frontiersin.org/article/10.3389/fmicb.2018.01446/full

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