Hematological profile of sickle cell disease from South Gujarat, India

The aim of this study was to determine hematological profile of sickle cell disease (SCD) from Surat, South Gujarat, India. This prospective cross-sectional study was conducted in the Department of Pediatrics and Sickle Cell Anemia Laboratory, Faculty of Pathology, Government Medical College, Surat,...

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Bibliographic Details
Main Authors: Sanjeev Shyam Rao, Jagdish Prasad Goyal, SV Raghunath, Vijay B. Shah
Format: Article
Language:English
Published: MDPI AG 2012-05-01
Series:Hematology Reports
Subjects:
Online Access:http://www.pagepress.org/journals/index.php/hr/article/view/4064
Description
Summary:The aim of this study was to determine hematological profile of sickle cell disease (SCD) from Surat, South Gujarat, India. This prospective cross-sectional study was conducted in the Department of Pediatrics and Sickle Cell Anemia Laboratory, Faculty of Pathology, Government Medical College, Surat, India, between July 2009 and December 2010. Patients included in this study were in their steady state for a long period of time without any symptoms related to SCD or other diseases which could affect the hematological parameters. Venous blood of all patients was collected in ethylenediaminetetraacetic acid and hematological indices were measured. Thirty-three subjects homozygous in all were studied for their hematological parameters for sickle cell anemia. Moderate to severe anemia, low mean cell volume and high foetal hemoglobin dominate the hematological profile of SCD children.
ISSN:2038-8322
2038-8330