A randomised clinical trial of subgrouping and targeted treatment for low back pain compared with best current care. The STarT Back Trial Study Protocol
<p>Abstract</p> <p>Background</p> <p>Back pain is a major health problem and many sufferers develop persistent symptoms. Detecting relevant subgroups of patients with non-specific low back pain has been highlighted as a priority area for research, as this could enable b...
| Main Authors: | , , , , , , , , , , |
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| Format: | Article |
| Language: | English |
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BMC
2008-04-01
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| Series: | BMC Musculoskeletal Disorders |
| Online Access: | http://www.biomedcentral.com/1471-2474/9/58 |
| _version_ | 1818766266738933760 |
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| author | Vohora Kanchan Somerville Simon Sowden Gail Konstantinou Kika Mason Elizabeth E Lewis Martyn Hill Jonathan C Dunn Kate M Hay Elaine M Whitehurst David Main Chris J |
| author_facet | Vohora Kanchan Somerville Simon Sowden Gail Konstantinou Kika Mason Elizabeth E Lewis Martyn Hill Jonathan C Dunn Kate M Hay Elaine M Whitehurst David Main Chris J |
| author_sort | Vohora Kanchan |
| collection | DOAJ |
| description | <p>Abstract</p> <p>Background</p> <p>Back pain is a major health problem and many sufferers develop persistent symptoms. Detecting relevant subgroups of patients with non-specific low back pain has been highlighted as a priority area for research, as this could enable better secondary prevention through the targeting of prognostic indicators for persistent, disabling symptoms. We plan to conduct a randomised controlled trial to establish whether subgrouping using a novel tool, combined with targeted treatment, is better than best current care at reducing long-term disability from low back pain.</p> <p>Methods/Design</p> <p>We will recruit 800 participants aged 18 years and over with non-specific low back pain from 8–10 GP practices within two Primary Care Trusts in Staffordshire, England. Our primary outcome measures are low back pain disability and catastrophising. Secondary outcomes include back pain intensity, global change, leg pain, fear avoidance, anxiety, depression, illness perceptions, patient satisfaction, overall health status and cost-effectiveness. Data will be collected before randomisation, and 4 and 12 months later. Participants are randomised to receive either newly developed interventions, delivered by trained physiotherapists and targeted according to subgroups defined by tool scores, or best current care.</p> <p>Discussion</p> <p>This paper presents detail on the rationale, design, methods and operational aspects of the trial.</p> <p>Trial registration</p> <p>Current Controlled Trials ISRCTN37113406.</p> |
| first_indexed | 2024-12-18T08:31:16Z |
| format | Article |
| id | doaj.art-7fdd631e0acc4b83b4debc0ac6e11096 |
| institution | Directory Open Access Journal |
| issn | 1471-2474 |
| language | English |
| last_indexed | 2024-12-18T08:31:16Z |
| publishDate | 2008-04-01 |
| publisher | BMC |
| record_format | Article |
| series | BMC Musculoskeletal Disorders |
| spelling | doaj.art-7fdd631e0acc4b83b4debc0ac6e110962022-12-21T21:14:27ZengBMCBMC Musculoskeletal Disorders1471-24742008-04-01915810.1186/1471-2474-9-58A randomised clinical trial of subgrouping and targeted treatment for low back pain compared with best current care. The STarT Back Trial Study ProtocolVohora KanchanSomerville SimonSowden GailKonstantinou KikaMason Elizabeth ELewis MartynHill Jonathan CDunn Kate MHay Elaine MWhitehurst DavidMain Chris J<p>Abstract</p> <p>Background</p> <p>Back pain is a major health problem and many sufferers develop persistent symptoms. Detecting relevant subgroups of patients with non-specific low back pain has been highlighted as a priority area for research, as this could enable better secondary prevention through the targeting of prognostic indicators for persistent, disabling symptoms. We plan to conduct a randomised controlled trial to establish whether subgrouping using a novel tool, combined with targeted treatment, is better than best current care at reducing long-term disability from low back pain.</p> <p>Methods/Design</p> <p>We will recruit 800 participants aged 18 years and over with non-specific low back pain from 8–10 GP practices within two Primary Care Trusts in Staffordshire, England. Our primary outcome measures are low back pain disability and catastrophising. Secondary outcomes include back pain intensity, global change, leg pain, fear avoidance, anxiety, depression, illness perceptions, patient satisfaction, overall health status and cost-effectiveness. Data will be collected before randomisation, and 4 and 12 months later. Participants are randomised to receive either newly developed interventions, delivered by trained physiotherapists and targeted according to subgroups defined by tool scores, or best current care.</p> <p>Discussion</p> <p>This paper presents detail on the rationale, design, methods and operational aspects of the trial.</p> <p>Trial registration</p> <p>Current Controlled Trials ISRCTN37113406.</p>http://www.biomedcentral.com/1471-2474/9/58 |
| spellingShingle | Vohora Kanchan Somerville Simon Sowden Gail Konstantinou Kika Mason Elizabeth E Lewis Martyn Hill Jonathan C Dunn Kate M Hay Elaine M Whitehurst David Main Chris J A randomised clinical trial of subgrouping and targeted treatment for low back pain compared with best current care. The STarT Back Trial Study Protocol BMC Musculoskeletal Disorders |
| title | A randomised clinical trial of subgrouping and targeted treatment for low back pain compared with best current care. The STarT Back Trial Study Protocol |
| title_full | A randomised clinical trial of subgrouping and targeted treatment for low back pain compared with best current care. The STarT Back Trial Study Protocol |
| title_fullStr | A randomised clinical trial of subgrouping and targeted treatment for low back pain compared with best current care. The STarT Back Trial Study Protocol |
| title_full_unstemmed | A randomised clinical trial of subgrouping and targeted treatment for low back pain compared with best current care. The STarT Back Trial Study Protocol |
| title_short | A randomised clinical trial of subgrouping and targeted treatment for low back pain compared with best current care. The STarT Back Trial Study Protocol |
| title_sort | randomised clinical trial of subgrouping and targeted treatment for low back pain compared with best current care the start back trial study protocol |
| url | http://www.biomedcentral.com/1471-2474/9/58 |
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