The Potential Roles of Actin in The Nucleus

Over the past few decades, actin’s presence in the nucleus has been demonstrated. Actin is a key protein necessary for different nuclear processes. Although actin is well known for its functional role in dynamic behavior of the cytoskeleton, emerging studies are now highlighting new roles for act...

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Main Authors: Khadijeh Falahzadeh, Amir Banaei-Esfahani, Maryam Shahhoseini
Format: Article
Language:English
Published: Royan Institute (ACECR), Tehran 2015-04-01
Series:Cell Journal
Subjects:
Online Access:http://celljournal.org/library/upload/article/af_2272253372237472845352323325522242274785Cell-J-17-7.pdf
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author Khadijeh Falahzadeh
Amir Banaei-Esfahani
Maryam Shahhoseini
author_facet Khadijeh Falahzadeh
Amir Banaei-Esfahani
Maryam Shahhoseini
author_sort Khadijeh Falahzadeh
collection DOAJ
description Over the past few decades, actin’s presence in the nucleus has been demonstrated. Actin is a key protein necessary for different nuclear processes. Although actin is well known for its functional role in dynamic behavior of the cytoskeleton, emerging studies are now highlighting new roles for actin. At the present time there is no doubt about the presence of actin in the nucleus. A number of studies have uncovered the functional involvement of actin in nuclear processes. Actin as one of the nuclear components has its own structured and functional rules, such as nuclear matrix association, chromatin remodeling, transcription by RNA polymerases I, II, III and mRNA processing. In this historical review, we attempt to provide an overview of our current understanding of the functions of actin in the nucleus.
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spelling doaj.art-7fddaecd8b6b4481a4de4c069047dbeb2022-12-21T21:51:50ZengRoyan Institute (ACECR), TehranCell Journal2228-58062228-58142015-04-01171714The Potential Roles of Actin in The NucleusKhadijeh Falahzadeh0Amir Banaei-Esfahani1Maryam Shahhoseini2Department of Genetics at Reproductive Biomedicine Research Center, Royan Institute for Reproductive Biomedicine, ACECR, Tehran, Iran . Department of Cell and Molecular Biology, Faculty of Biological Sciences, Kharazmi University (TMU), Tehran, IranDepartment of Biotechnology, College of Science, University of Tehran, Tehran, IranDepartment of Genetics at Reproductive Biomedicine Research Center, Royan Institute for Reproductive Biomedicine, ACECR, Tehran, IranOver the past few decades, actin’s presence in the nucleus has been demonstrated. Actin is a key protein necessary for different nuclear processes. Although actin is well known for its functional role in dynamic behavior of the cytoskeleton, emerging studies are now highlighting new roles for actin. At the present time there is no doubt about the presence of actin in the nucleus. A number of studies have uncovered the functional involvement of actin in nuclear processes. Actin as one of the nuclear components has its own structured and functional rules, such as nuclear matrix association, chromatin remodeling, transcription by RNA polymerases I, II, III and mRNA processing. In this historical review, we attempt to provide an overview of our current understanding of the functions of actin in the nucleus.http://celljournal.org/library/upload/article/af_2272253372237472845352323325522242274785Cell-J-17-7.pdfActinNuclear MatrixChromatin RemodelingTranscription
spellingShingle Khadijeh Falahzadeh
Amir Banaei-Esfahani
Maryam Shahhoseini
The Potential Roles of Actin in The Nucleus
Cell Journal
Actin
Nuclear Matrix
Chromatin Remodeling
Transcription
title The Potential Roles of Actin in The Nucleus
title_full The Potential Roles of Actin in The Nucleus
title_fullStr The Potential Roles of Actin in The Nucleus
title_full_unstemmed The Potential Roles of Actin in The Nucleus
title_short The Potential Roles of Actin in The Nucleus
title_sort potential roles of actin in the nucleus
topic Actin
Nuclear Matrix
Chromatin Remodeling
Transcription
url http://celljournal.org/library/upload/article/af_2272253372237472845352323325522242274785Cell-J-17-7.pdf
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