Distribution and effects of the muscarinic receptor subtypes in the primary visual cortex
Muscarinic cholinergic receptors modulate the activity and plasticity of the visual cortex. Muscarinic receptors are divided into 5 subtypes that are not homogeneously distributed throughout the cortical layers and cells types. This distribution results in complex action of the muscarinic receptors...
| Main Authors: | , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Frontiers Media S.A.
2015-06-01
|
| Series: | Frontiers in Synaptic Neuroscience |
| Subjects: | |
| Online Access: | http://journal.frontiersin.org/Journal/10.3389/fnsyn.2015.00010/full |
| _version_ | 1819104040667054080 |
|---|---|
| author | Marianne eGroleau Jun-Il eKang Frédéric eHuppé-Gourgues Elvire eVaucher |
| author_facet | Marianne eGroleau Jun-Il eKang Frédéric eHuppé-Gourgues Elvire eVaucher |
| author_sort | Marianne eGroleau |
| collection | DOAJ |
| description | Muscarinic cholinergic receptors modulate the activity and plasticity of the visual cortex. Muscarinic receptors are divided into 5 subtypes that are not homogeneously distributed throughout the cortical layers and cells types. This distribution results in complex action of the muscarinic receptors in the integration of visual stimuli. Selective activation of the different subtypes can either strengthen or weaken cortical connectivity (e.g., thalamocortical vs. corticocortical), i.e., it can influence the processing of certain stimuli over others. Moreover, muscarinic receptors differentially modulate some functional properties of neurons during experience-dependent activity and cognitive processes and they contribute to the fine-tuning of visual processing. These functions are involved in the mechanisms of attention, maturation and learning in the visual cortex. This minireview describes the anatomical-functional aspects of muscarinic modulation of the primary visual cortex’s microcircuitry. |
| first_indexed | 2024-12-22T02:00:02Z |
| format | Article |
| id | doaj.art-7fdeac67b2e341cd9f06a6333096b3d8 |
| institution | Directory Open Access Journal |
| issn | 1663-3563 |
| language | English |
| last_indexed | 2024-12-22T02:00:02Z |
| publishDate | 2015-06-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Synaptic Neuroscience |
| spelling | doaj.art-7fdeac67b2e341cd9f06a6333096b3d82022-12-21T18:42:40ZengFrontiers Media S.A.Frontiers in Synaptic Neuroscience1663-35632015-06-01710.3389/fnsyn.2015.00010147355Distribution and effects of the muscarinic receptor subtypes in the primary visual cortexMarianne eGroleau0Jun-Il eKang1Frédéric eHuppé-Gourgues2Elvire eVaucher3Université de MontréalUniversité de MontréalUniversité de MontréalUniversité de MontréalMuscarinic cholinergic receptors modulate the activity and plasticity of the visual cortex. Muscarinic receptors are divided into 5 subtypes that are not homogeneously distributed throughout the cortical layers and cells types. This distribution results in complex action of the muscarinic receptors in the integration of visual stimuli. Selective activation of the different subtypes can either strengthen or weaken cortical connectivity (e.g., thalamocortical vs. corticocortical), i.e., it can influence the processing of certain stimuli over others. Moreover, muscarinic receptors differentially modulate some functional properties of neurons during experience-dependent activity and cognitive processes and they contribute to the fine-tuning of visual processing. These functions are involved in the mechanisms of attention, maturation and learning in the visual cortex. This minireview describes the anatomical-functional aspects of muscarinic modulation of the primary visual cortex’s microcircuitry.http://journal.frontiersin.org/Journal/10.3389/fnsyn.2015.00010/fullAcetylcholineAttentionbasal forebraincholinergic systemGABAergic interneuronsprimary visual cortex (V1) |
| spellingShingle | Marianne eGroleau Jun-Il eKang Frédéric eHuppé-Gourgues Elvire eVaucher Distribution and effects of the muscarinic receptor subtypes in the primary visual cortex Frontiers in Synaptic Neuroscience Acetylcholine Attention basal forebrain cholinergic system GABAergic interneurons primary visual cortex (V1) |
| title | Distribution and effects of the muscarinic receptor subtypes in the primary visual cortex |
| title_full | Distribution and effects of the muscarinic receptor subtypes in the primary visual cortex |
| title_fullStr | Distribution and effects of the muscarinic receptor subtypes in the primary visual cortex |
| title_full_unstemmed | Distribution and effects of the muscarinic receptor subtypes in the primary visual cortex |
| title_short | Distribution and effects of the muscarinic receptor subtypes in the primary visual cortex |
| title_sort | distribution and effects of the muscarinic receptor subtypes in the primary visual cortex |
| topic | Acetylcholine Attention basal forebrain cholinergic system GABAergic interneurons primary visual cortex (V1) |
| url | http://journal.frontiersin.org/Journal/10.3389/fnsyn.2015.00010/full |
| work_keys_str_mv | AT marianneegroleau distributionandeffectsofthemuscarinicreceptorsubtypesintheprimaryvisualcortex AT junilekang distributionandeffectsofthemuscarinicreceptorsubtypesintheprimaryvisualcortex AT fredericehuppegourgues distributionandeffectsofthemuscarinicreceptorsubtypesintheprimaryvisualcortex AT elvireevaucher distributionandeffectsofthemuscarinicreceptorsubtypesintheprimaryvisualcortex |