Transforming growth factor-β-activated kinase 1 (TAK1) is required for human FcγRIIIb-induced neutrophil extracellular trap (NET) formation

Transforming growth factor-β-activated kinase 1 (TAK1) is required for human FcγRIIIb-induced neutrophil extracellular trap (NET) formation

Neutrophils (PMN) are the most abundant leukocytes in the blood. PMN migrate from the circulation to sites of infection, where they are responsible for antimicrobial functions. PMN use phagocytosis, degranulation, and formation of neutrophil extracellular traps (NETs) to kill microbes. Several stimu...

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Bibliographic Details
Main Authors: Omar Rafael Alemán, Nancy Mora, Ricarda Cortes-Vieyra, Eileen Uribe-Querol, CARLOS ROSALES
Format: Article
Language:English
Published: Frontiers Media S.A. 2016-07-01
Series:Frontiers in Immunology
Subjects:
DNA
Inflammation
ERK
Neutrophil
immunoglobulin
Immunoreceptor
Online Access:http://journal.frontiersin.org/Journal/10.3389/fimmu.2016.00277/full

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