Quality by Design Based Formulation of Xanthohumol Loaded Solid Lipid Nanoparticles with Improved Bioavailability and Anticancer Effect against PC-3 Cells

Quality by Design Based Formulation of Xanthohumol Loaded Solid Lipid Nanoparticles with Improved Bioavailability and Anticancer Effect against PC-3 Cells

Many natural products with greater therapeutic efficacy are limited to target several chronic diseases such as cancer, diabetes, and neurodegenerative diseases. Among the natural products from hops, i.e., Xanthohumol (XH), is a prenylated chalcone. The present research work focuses on the enhancemen...

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Bibliographic Details
Main Authors: Vancha Harish, Devesh Tewari, Sharfuddin Mohd, Pilli Govindaiah, Malakapogu Ravindra Babu, Rajesh Kumar, Monica Gulati, Kuppusamy Gowthamarajan, SubbaRao V. Madhunapantula, Dinesh Kumar Chellappan, Gaurav Gupta, Kamal Dua, Siva Dallavalasa, Sachin Kumar Singh
Format: Article
Language:English
Published: MDPI AG 2022-11-01
Series:Pharmaceutics
Subjects:
Box–Behnken Design
oral bioavailability
drug release
solid lipid nanoparticles
Xanthohumol
Online Access:https://www.mdpi.com/1999-4923/14/11/2403

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