Radiation Exposure to Low-Dose Computed Tomography for Lung Cancer Screening: Should We Be Concerned?
Lung cancer screening (LCS) programs through low-dose Computed Tomography (LDCT) are being implemented in several countries worldwide. Radiation exposure of healthy individuals due to prolonged CT screening rounds and, eventually, the additional examinations required in case of suspicious findings m...
| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
| Published: |
MDPI AG
2023-01-01
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| Series: | Tomography |
| Subjects: | |
| Online Access: | https://www.mdpi.com/2379-139X/9/1/15 |
| _version_ | 1797617996073533440 |
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| author | Chiara Pozzessere Christophe von Garnier Catherine Beigelman-Aubry |
| author_facet | Chiara Pozzessere Christophe von Garnier Catherine Beigelman-Aubry |
| author_sort | Chiara Pozzessere |
| collection | DOAJ |
| description | Lung cancer screening (LCS) programs through low-dose Computed Tomography (LDCT) are being implemented in several countries worldwide. Radiation exposure of healthy individuals due to prolonged CT screening rounds and, eventually, the additional examinations required in case of suspicious findings may represent a concern, thus eventually reducing the participation in an LCS program. Therefore, the present review aims to assess the potential radiation risk from LDCT in this setting, providing estimates of cumulative dose and radiation-related risk in LCS in order to improve awareness for an informed and complete attendance to the program. After summarizing the results of the international trials on LCS to introduce the benefits coming from the implementation of a dedicated program, the screening-related and participant-related factors determining the radiation risk will be introduced and their burden assessed. Finally, future directions for a personalized screening program as well as technical improvements to reduce the delivered dose will be presented. |
| first_indexed | 2024-03-11T08:03:54Z |
| format | Article |
| id | doaj.art-7ff11d5747da4ef784f8844482f0bf66 |
| institution | Directory Open Access Journal |
| issn | 2379-1381 2379-139X |
| language | English |
| last_indexed | 2024-03-11T08:03:54Z |
| publishDate | 2023-01-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Tomography |
| spelling | doaj.art-7ff11d5747da4ef784f8844482f0bf662023-11-16T23:36:28ZengMDPI AGTomography2379-13812379-139X2023-01-019116617710.3390/tomography9010015Radiation Exposure to Low-Dose Computed Tomography for Lung Cancer Screening: Should We Be Concerned?Chiara Pozzessere0Christophe von Garnier1Catherine Beigelman-Aubry2Department of Diagnostic and Interventional Radiology, Lausanne University Hospital (CHUV), 1011 Lausanne, SwitzerlandFaculty of Biology and Medicine, University of Lausanne (UNIL), 1011 Lausanne, SwitzerlandDepartment of Diagnostic and Interventional Radiology, Lausanne University Hospital (CHUV), 1011 Lausanne, SwitzerlandLung cancer screening (LCS) programs through low-dose Computed Tomography (LDCT) are being implemented in several countries worldwide. Radiation exposure of healthy individuals due to prolonged CT screening rounds and, eventually, the additional examinations required in case of suspicious findings may represent a concern, thus eventually reducing the participation in an LCS program. Therefore, the present review aims to assess the potential radiation risk from LDCT in this setting, providing estimates of cumulative dose and radiation-related risk in LCS in order to improve awareness for an informed and complete attendance to the program. After summarizing the results of the international trials on LCS to introduce the benefits coming from the implementation of a dedicated program, the screening-related and participant-related factors determining the radiation risk will be introduced and their burden assessed. Finally, future directions for a personalized screening program as well as technical improvements to reduce the delivered dose will be presented.https://www.mdpi.com/2379-139X/9/1/15computed tomographydiagnostic screening programsearly detectionlungneoplasmradiation dose-response relationship |
| spellingShingle | Chiara Pozzessere Christophe von Garnier Catherine Beigelman-Aubry Radiation Exposure to Low-Dose Computed Tomography for Lung Cancer Screening: Should We Be Concerned? Tomography computed tomography diagnostic screening programs early detection lung neoplasm radiation dose-response relationship |
| title | Radiation Exposure to Low-Dose Computed Tomography for Lung Cancer Screening: Should We Be Concerned? |
| title_full | Radiation Exposure to Low-Dose Computed Tomography for Lung Cancer Screening: Should We Be Concerned? |
| title_fullStr | Radiation Exposure to Low-Dose Computed Tomography for Lung Cancer Screening: Should We Be Concerned? |
| title_full_unstemmed | Radiation Exposure to Low-Dose Computed Tomography for Lung Cancer Screening: Should We Be Concerned? |
| title_short | Radiation Exposure to Low-Dose Computed Tomography for Lung Cancer Screening: Should We Be Concerned? |
| title_sort | radiation exposure to low dose computed tomography for lung cancer screening should we be concerned |
| topic | computed tomography diagnostic screening programs early detection lung neoplasm radiation dose-response relationship |
| url | https://www.mdpi.com/2379-139X/9/1/15 |
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