Ionophore-Based Potassium Selective Fluorescent Organosilica Nano-Optodes Containing Covalently Attached Solvatochromic Dyes
Fluorescent nanoprobes containing ionophores and solvatochromic dyes (SDs) were previously reported as an alternative to chromoionophore-based nano-optodes. However, the small-molecular SDs are prone to leakage and sequestration in complex samples. Here, we chemically attached the SDs to the surface...
Main Authors: | , , |
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Format: | Article |
Language: | English |
Published: |
MDPI AG
2022-01-01
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Series: | Chemosensors |
Subjects: | |
Online Access: | https://www.mdpi.com/2227-9040/10/1/23 |
Summary: | Fluorescent nanoprobes containing ionophores and solvatochromic dyes (SDs) were previously reported as an alternative to chromoionophore-based nano-optodes. However, the small-molecular SDs are prone to leakage and sequestration in complex samples. Here, we chemically attached the SDs to the surface of organosilica nanospheres through copper-catalyzed Click chemistry to prevent dye leakage. The nano-optodes remained well responsive to K<sup>+</sup> even after exposure to a large amount of cation-exchange resin, which acted as a sink of the SDs. The potassium nanoprobes exhibited a dynamic range between 1 μM to 10 mM and a good selectivity thanks to valinomycin. Preliminary sensing device based on a nylon filter paper and agarose hydrogel was demonstrated. The results indicate that the covalent anchoring of SDs on nanospheres is promising for developing ionophore-based nanoprobes. |
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ISSN: | 2227-9040 |