LPMO as a Key Enzyme in the Sustainable Conversion of Lignocellulosic Biomass
The importance of the lytic polysaccharide monooxygenase (LPMO) enzyme in the preparation of lignocellulosic raw materials for production in biorefineries has been confirmed in numerous investigations. Therefore, LPMO enzymes were investigated to explore the enzyme-substrate interaction with the aim...
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Format: | Article |
Language: | English |
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Croatian Society of Chemical Engineers
2023-05-01
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Series: | Kemija u Industriji |
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Online Access: | http://silverstripe.fkit.hr/kui/assets/Uploads/12-389-395-KUI-5-6-2023.pdf |
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author | Tonči Rezić Martina Andlar Ana Vrsalović Presečki |
author_facet | Tonči Rezić Martina Andlar Ana Vrsalović Presečki |
author_sort | Tonči Rezić |
collection | DOAJ |
description | The importance of the lytic polysaccharide monooxygenase (LPMO) enzyme in the preparation of lignocellulosic raw materials for production in biorefineries has been confirmed in numerous investigations. Therefore, LPMO enzymes were investigated to explore the enzyme-substrate interaction with the aim of successful biomass conversion in biorefinery processes. After reductive activation of LPMOs active site, they cleave the substrate and prepare it for biomass degradation by hydrolytic enzymes. In this paper, the role of LPMO in lignocellulosic biomass conversion is described based on the recent studies of: LPMO enzyme structure, LPMO substrate preferences, and the LPMO reaction mechanism. These findings are important for the selection of suitable bioprocess conditions with the aim of LPMO activation/stabilisation in biorefinery production processes. |
first_indexed | 2024-03-13T10:57:30Z |
format | Article |
id | doaj.art-7ff3790448d3448593da96811699ff89 |
institution | Directory Open Access Journal |
issn | 0022-9830 1334-9090 |
language | English |
last_indexed | 2024-03-13T10:57:30Z |
publishDate | 2023-05-01 |
publisher | Croatian Society of Chemical Engineers |
record_format | Article |
series | Kemija u Industriji |
spelling | doaj.art-7ff3790448d3448593da96811699ff892023-05-16T23:38:10ZengCroatian Society of Chemical EngineersKemija u Industriji0022-98301334-90902023-05-01725-638939510.15255/KUI.2023.010LPMO as a Key Enzyme in the Sustainable Conversion of Lignocellulosic BiomassTonči Rezić0Martina Andlar1Ana Vrsalović Presečki2University of Zagreb, Faculty of Food Technology and Biotechnology, Pierottijeva 6, 10 000 Zagreb, CroatiaUniversity of Zagreb, Faculty of Food Technology and Biotechnology, Pierottijeva 6, 10 000 Zagreb, CroatiaUniversity of Zagreb, Faculty of Chemical Engineering and Technology, Trg Marka Marulića 19, 10 000 Zagreb, CroatiaThe importance of the lytic polysaccharide monooxygenase (LPMO) enzyme in the preparation of lignocellulosic raw materials for production in biorefineries has been confirmed in numerous investigations. Therefore, LPMO enzymes were investigated to explore the enzyme-substrate interaction with the aim of successful biomass conversion in biorefinery processes. After reductive activation of LPMOs active site, they cleave the substrate and prepare it for biomass degradation by hydrolytic enzymes. In this paper, the role of LPMO in lignocellulosic biomass conversion is described based on the recent studies of: LPMO enzyme structure, LPMO substrate preferences, and the LPMO reaction mechanism. These findings are important for the selection of suitable bioprocess conditions with the aim of LPMO activation/stabilisation in biorefinery production processes.http://silverstripe.fkit.hr/kui/assets/Uploads/12-389-395-KUI-5-6-2023.pdflytic polysaccharide monooxygenasesubstratelignocellulosic biomassreaction mechanismenzymatic hydrolysis |
spellingShingle | Tonči Rezić Martina Andlar Ana Vrsalović Presečki LPMO as a Key Enzyme in the Sustainable Conversion of Lignocellulosic Biomass Kemija u Industriji lytic polysaccharide monooxygenase substrate lignocellulosic biomass reaction mechanism enzymatic hydrolysis |
title | LPMO as a Key Enzyme in the Sustainable Conversion of Lignocellulosic Biomass |
title_full | LPMO as a Key Enzyme in the Sustainable Conversion of Lignocellulosic Biomass |
title_fullStr | LPMO as a Key Enzyme in the Sustainable Conversion of Lignocellulosic Biomass |
title_full_unstemmed | LPMO as a Key Enzyme in the Sustainable Conversion of Lignocellulosic Biomass |
title_short | LPMO as a Key Enzyme in the Sustainable Conversion of Lignocellulosic Biomass |
title_sort | lpmo as a key enzyme in the sustainable conversion of lignocellulosic biomass |
topic | lytic polysaccharide monooxygenase substrate lignocellulosic biomass reaction mechanism enzymatic hydrolysis |
url | http://silverstripe.fkit.hr/kui/assets/Uploads/12-389-395-KUI-5-6-2023.pdf |
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