Vitamin D Status in Renal Transplant recipients is not Associated with Erectile Dysfunction
Erectile dysfunction (ED) is a highly prevalent disorder among renal transplant recipients. Vitamin D deficiency (VDD) has been associated with several ED risk factors but only recently directly linked to ED. We conducted a study to investigate whether vitamin D serum levels were associated with the...
| Main Authors: | , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Sestre Milosrdnice University hospital, Institute of Clinical Medical Research
2017-01-01
|
| Series: | Acta Clinica Croatica |
| Subjects: | |
| Online Access: | https://hrcak.srce.hr/file/274879 |
| _version_ | 1797207818476978176 |
|---|---|
| author | Bojan Sudarević Ivana Begić Dalibor Šimunović Hrvoje Kuveždić Vatroslav Šerić Lada Zibar |
| author_facet | Bojan Sudarević Ivana Begić Dalibor Šimunović Hrvoje Kuveždić Vatroslav Šerić Lada Zibar |
| author_sort | Bojan Sudarević |
| collection | DOAJ |
| description | Erectile dysfunction (ED) is a highly prevalent disorder among renal transplant recipients. Vitamin D deficiency (VDD) has been associated with several ED risk factors but only recently directly linked to ED. We conducted a study to investigate whether vitamin D serum levels were associated with the presence and severity of ED in 40 male patients that underwent deceased donor kidney transplantation (TX) from 2001 to 2013. Blood samples were collected on two seasonally distinct occasions and 25(OH)D concentration was assessed by radioimmunoassay. A 5-item version of the International Index of Erectile Function (IIEF-5) was used for ED evaluation and group stratification. We found comparable rates of ED (75%) and VDD (42.5%-62.5%) as in previously published studies. Serum levels of 25(OH)D did not differ between patients with and those without ED on both measurements (p=0.656 and p=0.914, respectively), or when comparing different ED severity groups. Duration of renal replacement therapy before TX and graft duration until analysis were longer in patients with ED (p=0.022 and p=0.05, respectively), but with the results being nonsignificant on logistic regression. In conclusion, we found no association of 25(OH)D concentration with the presence and severity of ED in renal transplant recipients. So far, there are no similar published data. |
| first_indexed | 2024-04-24T09:28:57Z |
| format | Article |
| id | doaj.art-7ff5449ad4c24d94934cf2c1f1e11798 |
| institution | Directory Open Access Journal |
| issn | 0353-9466 1333-9451 |
| language | English |
| last_indexed | 2024-04-24T09:28:57Z |
| publishDate | 2017-01-01 |
| publisher | Sestre Milosrdnice University hospital, Institute of Clinical Medical Research |
| record_format | Article |
| series | Acta Clinica Croatica |
| spelling | doaj.art-7ff5449ad4c24d94934cf2c1f1e117982024-04-15T14:21:56ZengSestre Milosrdnice University hospital, Institute of Clinical Medical ResearchActa Clinica Croatica0353-94661333-94512017-01-0156.2.19520210.20471/acc.2017.56.02.01Vitamin D Status in Renal Transplant recipients is not Associated with Erectile DysfunctionBojan Sudarević0Ivana Begić1Dalibor Šimunović2Hrvoje Kuveždić3Vatroslav Šerić4Lada Zibar5Department of Urology, Osijek University Hospital Center; School of Medicine, Josip Juraj Strossmayer University of OsijekDepartment of Dialysis, Clinical Department of Internal Medicine, Osijek University Hospital Center; Department of Physiology and Immunology, School of Medicine, Josip Juraj Strossmayer University of OsijekDepartment of Urology, Osijek University Hospital Center; School of Medicine, Josip Juraj Strossmayer University of OsijekDepartment of Urology, Osijek University Hospital Center; School of Medicine, Josip Juraj Strossmayer University of OsijekDepartment of Clinical Laboratory Diagnosis, Osijek University Hospital Center; School of Medicine, Josip Juraj Strossmayer University of OsijekDepartment of Dialysis, Clinical Department of Internal Medicine, Osijek University Hospital Center; Department of Pathophysiology, School of Medicine, Josip Juraj Strossmayer University of Osijek, Osijek, CroatiaErectile dysfunction (ED) is a highly prevalent disorder among renal transplant recipients. Vitamin D deficiency (VDD) has been associated with several ED risk factors but only recently directly linked to ED. We conducted a study to investigate whether vitamin D serum levels were associated with the presence and severity of ED in 40 male patients that underwent deceased donor kidney transplantation (TX) from 2001 to 2013. Blood samples were collected on two seasonally distinct occasions and 25(OH)D concentration was assessed by radioimmunoassay. A 5-item version of the International Index of Erectile Function (IIEF-5) was used for ED evaluation and group stratification. We found comparable rates of ED (75%) and VDD (42.5%-62.5%) as in previously published studies. Serum levels of 25(OH)D did not differ between patients with and those without ED on both measurements (p=0.656 and p=0.914, respectively), or when comparing different ED severity groups. Duration of renal replacement therapy before TX and graft duration until analysis were longer in patients with ED (p=0.022 and p=0.05, respectively), but with the results being nonsignificant on logistic regression. In conclusion, we found no association of 25(OH)D concentration with the presence and severity of ED in renal transplant recipients. So far, there are no similar published data.https://hrcak.srce.hr/file/274879Vitamin D deficiencyErectile dysfunctionEndothelium, vascularRenal insufficiency, chronicKidney transplantationCroatia |
| spellingShingle | Bojan Sudarević Ivana Begić Dalibor Šimunović Hrvoje Kuveždić Vatroslav Šerić Lada Zibar Vitamin D Status in Renal Transplant recipients is not Associated with Erectile Dysfunction Acta Clinica Croatica Vitamin D deficiency Erectile dysfunction Endothelium, vascular Renal insufficiency, chronic Kidney transplantation Croatia |
| title | Vitamin D Status in Renal Transplant recipients is not Associated with Erectile Dysfunction |
| title_full | Vitamin D Status in Renal Transplant recipients is not Associated with Erectile Dysfunction |
| title_fullStr | Vitamin D Status in Renal Transplant recipients is not Associated with Erectile Dysfunction |
| title_full_unstemmed | Vitamin D Status in Renal Transplant recipients is not Associated with Erectile Dysfunction |
| title_short | Vitamin D Status in Renal Transplant recipients is not Associated with Erectile Dysfunction |
| title_sort | vitamin d status in renal transplant recipients is not associated with erectile dysfunction |
| topic | Vitamin D deficiency Erectile dysfunction Endothelium, vascular Renal insufficiency, chronic Kidney transplantation Croatia |
| url | https://hrcak.srce.hr/file/274879 |
| work_keys_str_mv | AT bojansudarevic vitamindstatusinrenaltransplantrecipientsisnotassociatedwitherectiledysfunction AT ivanabegic vitamindstatusinrenaltransplantrecipientsisnotassociatedwitherectiledysfunction AT daliborsimunovic vitamindstatusinrenaltransplantrecipientsisnotassociatedwitherectiledysfunction AT hrvojekuvezdic vitamindstatusinrenaltransplantrecipientsisnotassociatedwitherectiledysfunction AT vatroslavseric vitamindstatusinrenaltransplantrecipientsisnotassociatedwitherectiledysfunction AT ladazibar vitamindstatusinrenaltransplantrecipientsisnotassociatedwitherectiledysfunction |