Seroprevalence of Visceral Leishmaniasis in Children up to 12 Years old Among Nomadic Tribes from Rural Areas of Pars Abad, Northwestern Iran: an Observational Study in 2015
Background: Since Pars Abad district had been known as a focus of visceral leishmaniasis (VL) in Ardabil Province but the prevalence of the disease in nomadic tribes has not been determined, thus, this study was conducted. Methods: This descriptive cross- sectional study was conducted on children u...
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| Format: | Article |
| Language: | English |
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Tehran University of Medical Sciences
2017-06-01
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| Series: | Journal of Arthropod-Borne Diseases |
| Subjects: | |
| Online Access: | https://jad.tums.ac.ir/index.php/jad/article/view/652 |
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| author | Hasan Ebrahimzade-Parikhani Mehdi Mohebali Zabiholah Zarei Behnaz Akhoundi Zahra Kakoei |
| author_facet | Hasan Ebrahimzade-Parikhani Mehdi Mohebali Zabiholah Zarei Behnaz Akhoundi Zahra Kakoei |
| author_sort | Hasan Ebrahimzade-Parikhani |
| collection | DOAJ |
| description | Background: Since Pars Abad district had been known as a focus of visceral leishmaniasis (VL) in Ardabil Province but the prevalence of the disease in nomadic tribes has not been determined, thus, this study was conducted.
Methods: This descriptive cross- sectional study was conducted on children up to 12yr old of nomadic tribes from Pars Abad County, Ardabil Province, Iran in 2015. For each individual, a questionnaire including age, sex, clinical manifestations, history of disease, and contact with reservoir hosts of VL were completed, separately. To determine VL seroprevalence, blood samples were collected from the children and after centrifugation, the plasma samples were tested using Direct Agglutination Test (DAT) for detection of anti-Leishmania infantum antibodies. Statistical analyses were performed using SPSS16.
Results: From 776 children up to 12yr old, 2 (0.25%) showed anti-L. infantum antibodies at titers 1:1600 and only one case (0.13%) showed anti-Leishmania antibodies at titers 1:3200. The child with anti-L. infantum antibodies titers of 1:3200 showed mild fever for more than 2 months period, paleness, weakness and mild splenomegaly. After physical examination and confirmation of VL (kala-azar), the patient was treated with antileishmanial drugs.
Conclusion: The findings indicated that L. infantum infection is being circulated with low prevalence in nomadic tribes of Pars Abad but it is necessary that the surveillance system is regularly monitored among physicians and public health managers in the studied areas. |
| first_indexed | 2024-12-11T11:56:28Z |
| format | Article |
| id | doaj.art-7ff6085683f24e6f8a046988d7d94432 |
| institution | Directory Open Access Journal |
| issn | 1735-7179 2322-2271 |
| language | English |
| last_indexed | 2024-12-11T11:56:28Z |
| publishDate | 2017-06-01 |
| publisher | Tehran University of Medical Sciences |
| record_format | Article |
| series | Journal of Arthropod-Borne Diseases |
| spelling | doaj.art-7ff6085683f24e6f8a046988d7d944322022-12-22T01:08:11ZengTehran University of Medical SciencesJournal of Arthropod-Borne Diseases1735-71792322-22712017-06-01112347Seroprevalence of Visceral Leishmaniasis in Children up to 12 Years old Among Nomadic Tribes from Rural Areas of Pars Abad, Northwestern Iran: an Observational Study in 2015Hasan Ebrahimzade-Parikhani0Mehdi Mohebali1Zabiholah Zarei2Behnaz Akhoundi3Zahra Kakoei4Department of Medical Parasitology and Mycology, School of Public Health, Tehran University of Medical Sciences, Tehran, Iran Center for Research of Endemic Parasites of Iran, Tehran University of Medical Sciences, Tehran, IranDepartment of Medical Parasitology and Mycology, School of Public Health, Tehran University of Medical Sciences, Tehran, IranDepartment of Medical Parasitology and Mycology, School of Public Health, Tehran University of Medical Sciences, Tehran, IranDepartment of Medical Parasitology and Mycology, School of Public Health, Tehran University of Medical Sciences, Tehran, IranDepartment of Medical Parasitology and Mycology, School of Public Health, Tehran University of Medical Sciences, Tehran, IranBackground: Since Pars Abad district had been known as a focus of visceral leishmaniasis (VL) in Ardabil Province but the prevalence of the disease in nomadic tribes has not been determined, thus, this study was conducted. Methods: This descriptive cross- sectional study was conducted on children up to 12yr old of nomadic tribes from Pars Abad County, Ardabil Province, Iran in 2015. For each individual, a questionnaire including age, sex, clinical manifestations, history of disease, and contact with reservoir hosts of VL were completed, separately. To determine VL seroprevalence, blood samples were collected from the children and after centrifugation, the plasma samples were tested using Direct Agglutination Test (DAT) for detection of anti-Leishmania infantum antibodies. Statistical analyses were performed using SPSS16. Results: From 776 children up to 12yr old, 2 (0.25%) showed anti-L. infantum antibodies at titers 1:1600 and only one case (0.13%) showed anti-Leishmania antibodies at titers 1:3200. The child with anti-L. infantum antibodies titers of 1:3200 showed mild fever for more than 2 months period, paleness, weakness and mild splenomegaly. After physical examination and confirmation of VL (kala-azar), the patient was treated with antileishmanial drugs. Conclusion: The findings indicated that L. infantum infection is being circulated with low prevalence in nomadic tribes of Pars Abad but it is necessary that the surveillance system is regularly monitored among physicians and public health managers in the studied areas.https://jad.tums.ac.ir/index.php/jad/article/view/652Sero-prevalenceVisceral leishmaniasisNomadic tribesChildrenIran |
| spellingShingle | Hasan Ebrahimzade-Parikhani Mehdi Mohebali Zabiholah Zarei Behnaz Akhoundi Zahra Kakoei Seroprevalence of Visceral Leishmaniasis in Children up to 12 Years old Among Nomadic Tribes from Rural Areas of Pars Abad, Northwestern Iran: an Observational Study in 2015 Journal of Arthropod-Borne Diseases Sero-prevalence Visceral leishmaniasis Nomadic tribes Children Iran |
| title | Seroprevalence of Visceral Leishmaniasis in Children up to 12 Years old Among Nomadic Tribes from Rural Areas of Pars Abad, Northwestern Iran: an Observational Study in 2015 |
| title_full | Seroprevalence of Visceral Leishmaniasis in Children up to 12 Years old Among Nomadic Tribes from Rural Areas of Pars Abad, Northwestern Iran: an Observational Study in 2015 |
| title_fullStr | Seroprevalence of Visceral Leishmaniasis in Children up to 12 Years old Among Nomadic Tribes from Rural Areas of Pars Abad, Northwestern Iran: an Observational Study in 2015 |
| title_full_unstemmed | Seroprevalence of Visceral Leishmaniasis in Children up to 12 Years old Among Nomadic Tribes from Rural Areas of Pars Abad, Northwestern Iran: an Observational Study in 2015 |
| title_short | Seroprevalence of Visceral Leishmaniasis in Children up to 12 Years old Among Nomadic Tribes from Rural Areas of Pars Abad, Northwestern Iran: an Observational Study in 2015 |
| title_sort | seroprevalence of visceral leishmaniasis in children up to 12 years old among nomadic tribes from rural areas of pars abad northwestern iran an observational study in 2015 |
| topic | Sero-prevalence Visceral leishmaniasis Nomadic tribes Children Iran |
| url | https://jad.tums.ac.ir/index.php/jad/article/view/652 |
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