The frequency of early age-related macular degeneration and its relationship with dietary pattern in Hunan, China: a cross-sectional study
Abstract Purpose To estimate the frequency of age-related macular degeneration (AMD) among people who underwent health examination in Hunan, China and to determine the relationship between dietary pattern and the risk of AMD. Methods The Questionnaire was used to collect dietary data from 56,775 stu...
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| Format: | Article |
| Language: | English |
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BMC
2022-07-01
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| Series: | BMC Ophthalmology |
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| Online Access: | https://doi.org/10.1186/s12886-022-02549-x |
| _version_ | 1818162594994716672 |
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| author | Yanhui Lin Ting Peng Ying Li Yu Liu |
| author_facet | Yanhui Lin Ting Peng Ying Li Yu Liu |
| author_sort | Yanhui Lin |
| collection | DOAJ |
| description | Abstract Purpose To estimate the frequency of age-related macular degeneration (AMD) among people who underwent health examination in Hunan, China and to determine the relationship between dietary pattern and the risk of AMD. Methods The Questionnaire was used to collect dietary data from 56,775 study participants of ≥ 50 years old who underwent health examination at the Department of Health Management, the Third Xiangya Hospital of Central South University between January 2017 and December 2019. The diagnosis of AMD was based on the results of color fundus photography (CFP), spectral-domain optical coherence tomography (OCT) and multispectral imaging (MSI). After excluding participants with incomplete records or other ocular disease that may affect the results of fundus examination, a total of 43,672 study participants were included. The univariate and multivariate logistic regression analyses were used to determine the relationship between dietary pattern and the frequency of AMD. Results Among the 43,672 study participants, 1080 (2.5%) had early AMD: the frequencies were 2.6% (n = 674) in men and 2.3% (n = 406) in women; the frequencies were 1.0% (n = 289), 3.6% (n = 401), 9.1% (n = 390) in 50–59, 60–69, ≥ 70 years old, respectively. And the age-standard frequency was 6.6% over the 60 years old in Hunan China. The high-salt intake increased the risk of early AMD [odds ratio (OR) = 1.61, 95% confidence interval (CI) = 1.54–1.68], whereas the intake of meat decreased the risk (OR = 0.90, 95% CI = 0.81–0.99). Conclusion In Hunan China, there was a high frequency of early AMD detected through health examination over the 60 years old. And high-salt intake increases the risk of early AMD, whereas intake of meat decreases the risk. Modulating the dietary pattern and reducing the salt intake as an AMD prevention strategy warrant further study. |
| first_indexed | 2024-12-11T16:36:09Z |
| format | Article |
| id | doaj.art-7ff84eb401d94c9ca26a7f044a20fb72 |
| institution | Directory Open Access Journal |
| issn | 1471-2415 |
| language | English |
| last_indexed | 2024-12-11T16:36:09Z |
| publishDate | 2022-07-01 |
| publisher | BMC |
| record_format | Article |
| series | BMC Ophthalmology |
| spelling | doaj.art-7ff84eb401d94c9ca26a7f044a20fb722022-12-22T00:58:27ZengBMCBMC Ophthalmology1471-24152022-07-0122111110.1186/s12886-022-02549-xThe frequency of early age-related macular degeneration and its relationship with dietary pattern in Hunan, China: a cross-sectional studyYanhui Lin0Ting Peng1Ying Li2Yu Liu3Health Management Center, The Third Xiangya Hospital, Central South UniversityHealth Management Center, The Third Xiangya Hospital, Central South UniversityHealth Management Center, The Third Xiangya Hospital, Central South UniversityDepartment of Ophthalmology, The Third Xiangya Hospital, Central South UniversityAbstract Purpose To estimate the frequency of age-related macular degeneration (AMD) among people who underwent health examination in Hunan, China and to determine the relationship between dietary pattern and the risk of AMD. Methods The Questionnaire was used to collect dietary data from 56,775 study participants of ≥ 50 years old who underwent health examination at the Department of Health Management, the Third Xiangya Hospital of Central South University between January 2017 and December 2019. The diagnosis of AMD was based on the results of color fundus photography (CFP), spectral-domain optical coherence tomography (OCT) and multispectral imaging (MSI). After excluding participants with incomplete records or other ocular disease that may affect the results of fundus examination, a total of 43,672 study participants were included. The univariate and multivariate logistic regression analyses were used to determine the relationship between dietary pattern and the frequency of AMD. Results Among the 43,672 study participants, 1080 (2.5%) had early AMD: the frequencies were 2.6% (n = 674) in men and 2.3% (n = 406) in women; the frequencies were 1.0% (n = 289), 3.6% (n = 401), 9.1% (n = 390) in 50–59, 60–69, ≥ 70 years old, respectively. And the age-standard frequency was 6.6% over the 60 years old in Hunan China. The high-salt intake increased the risk of early AMD [odds ratio (OR) = 1.61, 95% confidence interval (CI) = 1.54–1.68], whereas the intake of meat decreased the risk (OR = 0.90, 95% CI = 0.81–0.99). Conclusion In Hunan China, there was a high frequency of early AMD detected through health examination over the 60 years old. And high-salt intake increases the risk of early AMD, whereas intake of meat decreases the risk. Modulating the dietary pattern and reducing the salt intake as an AMD prevention strategy warrant further study.https://doi.org/10.1186/s12886-022-02549-xAge-related macular degenerationDietary patternFrequencySalt intakeHealth examination |
| spellingShingle | Yanhui Lin Ting Peng Ying Li Yu Liu The frequency of early age-related macular degeneration and its relationship with dietary pattern in Hunan, China: a cross-sectional study BMC Ophthalmology Age-related macular degeneration Dietary pattern Frequency Salt intake Health examination |
| title | The frequency of early age-related macular degeneration and its relationship with dietary pattern in Hunan, China: a cross-sectional study |
| title_full | The frequency of early age-related macular degeneration and its relationship with dietary pattern in Hunan, China: a cross-sectional study |
| title_fullStr | The frequency of early age-related macular degeneration and its relationship with dietary pattern in Hunan, China: a cross-sectional study |
| title_full_unstemmed | The frequency of early age-related macular degeneration and its relationship with dietary pattern in Hunan, China: a cross-sectional study |
| title_short | The frequency of early age-related macular degeneration and its relationship with dietary pattern in Hunan, China: a cross-sectional study |
| title_sort | frequency of early age related macular degeneration and its relationship with dietary pattern in hunan china a cross sectional study |
| topic | Age-related macular degeneration Dietary pattern Frequency Salt intake Health examination |
| url | https://doi.org/10.1186/s12886-022-02549-x |
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