Isolated testicular tuberculosis with ethambutol cutaneous toxicity: A combination of two rare entities

Tuberculosis (TB) is an infection that can affect any organ, affecting mainly the lungs. Isolated testicular TB is very rare. Six months of a multiple drug scheme is the mainstay of TB treatment. Adverse reaction to anti-TB chemotherapy is frequent and affects the course of the therapy, leading some...

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Bibliographic Details
Main Authors: Flávio Godinho Pereira, Mariana da Silva Leal, Susana Cavadas, Inês Ladeira
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2020-01-01
Series:International Journal of Mycobacteriology
Subjects:
Online Access:http://www.ijmyco.org/article.asp?issn=2212-5531;year=2020;volume=9;issue=3;spage=322;epage=324;aulast=Pereira
Description
Summary:Tuberculosis (TB) is an infection that can affect any organ, affecting mainly the lungs. Isolated testicular TB is very rare. Six months of a multiple drug scheme is the mainstay of TB treatment. Adverse reaction to anti-TB chemotherapy is frequent and affects the course of the therapy, leading sometimes to discontinuation of drugs. Ethambutol optic nerve toxicity is frequent. However, severe cutaneous and anaphylactic reactions associated to ethambutol are very rare. We present the case of an immunocompetent patient presenting with isolated testicular TB that exhibited a severe cutaneous and anaphylactic reaction to ethambutol during the consolidation treatment phase. This led to exhaustive etiologic study and treatment modification.
ISSN:2212-5531
2212-554X