Isolated testicular tuberculosis with ethambutol cutaneous toxicity: A combination of two rare entities
Tuberculosis (TB) is an infection that can affect any organ, affecting mainly the lungs. Isolated testicular TB is very rare. Six months of a multiple drug scheme is the mainstay of TB treatment. Adverse reaction to anti-TB chemotherapy is frequent and affects the course of the therapy, leading some...
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Format: | Article |
Language: | English |
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Wolters Kluwer Medknow Publications
2020-01-01
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Series: | International Journal of Mycobacteriology |
Subjects: | |
Online Access: | http://www.ijmyco.org/article.asp?issn=2212-5531;year=2020;volume=9;issue=3;spage=322;epage=324;aulast=Pereira |
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author | Flávio Godinho Pereira Mariana da Silva Leal Susana Cavadas Inês Ladeira |
author_facet | Flávio Godinho Pereira Mariana da Silva Leal Susana Cavadas Inês Ladeira |
author_sort | Flávio Godinho Pereira |
collection | DOAJ |
description | Tuberculosis (TB) is an infection that can affect any organ, affecting mainly the lungs. Isolated testicular TB is very rare. Six months of a multiple drug scheme is the mainstay of TB treatment. Adverse reaction to anti-TB chemotherapy is frequent and affects the course of the therapy, leading sometimes to discontinuation of drugs. Ethambutol optic nerve toxicity is frequent. However, severe cutaneous and anaphylactic reactions associated to ethambutol are very rare. We present the case of an immunocompetent patient presenting with isolated testicular TB that exhibited a severe cutaneous and anaphylactic reaction to ethambutol during the consolidation treatment phase. This led to exhaustive etiologic study and treatment modification. |
first_indexed | 2024-12-11T12:10:05Z |
format | Article |
id | doaj.art-7ff9646c2340496eab2e594ab7b54513 |
institution | Directory Open Access Journal |
issn | 2212-5531 2212-554X |
language | English |
last_indexed | 2024-12-11T12:10:05Z |
publishDate | 2020-01-01 |
publisher | Wolters Kluwer Medknow Publications |
record_format | Article |
series | International Journal of Mycobacteriology |
spelling | doaj.art-7ff9646c2340496eab2e594ab7b545132022-12-22T01:07:50ZengWolters Kluwer Medknow PublicationsInternational Journal of Mycobacteriology2212-55312212-554X2020-01-019332232410.4103/ijmy.ijmy_114_20Isolated testicular tuberculosis with ethambutol cutaneous toxicity: A combination of two rare entitiesFlávio Godinho PereiraMariana da Silva LealSusana CavadasInês LadeiraTuberculosis (TB) is an infection that can affect any organ, affecting mainly the lungs. Isolated testicular TB is very rare. Six months of a multiple drug scheme is the mainstay of TB treatment. Adverse reaction to anti-TB chemotherapy is frequent and affects the course of the therapy, leading sometimes to discontinuation of drugs. Ethambutol optic nerve toxicity is frequent. However, severe cutaneous and anaphylactic reactions associated to ethambutol are very rare. We present the case of an immunocompetent patient presenting with isolated testicular TB that exhibited a severe cutaneous and anaphylactic reaction to ethambutol during the consolidation treatment phase. This led to exhaustive etiologic study and treatment modification.http://www.ijmyco.org/article.asp?issn=2212-5531;year=2020;volume=9;issue=3;spage=322;epage=324;aulast=Pereiracutaneous toxicityethambutolextrapulmonary tuberculosistesticular tuberculosis |
spellingShingle | Flávio Godinho Pereira Mariana da Silva Leal Susana Cavadas Inês Ladeira Isolated testicular tuberculosis with ethambutol cutaneous toxicity: A combination of two rare entities International Journal of Mycobacteriology cutaneous toxicity ethambutol extrapulmonary tuberculosis testicular tuberculosis |
title | Isolated testicular tuberculosis with ethambutol cutaneous toxicity: A combination of two rare entities |
title_full | Isolated testicular tuberculosis with ethambutol cutaneous toxicity: A combination of two rare entities |
title_fullStr | Isolated testicular tuberculosis with ethambutol cutaneous toxicity: A combination of two rare entities |
title_full_unstemmed | Isolated testicular tuberculosis with ethambutol cutaneous toxicity: A combination of two rare entities |
title_short | Isolated testicular tuberculosis with ethambutol cutaneous toxicity: A combination of two rare entities |
title_sort | isolated testicular tuberculosis with ethambutol cutaneous toxicity a combination of two rare entities |
topic | cutaneous toxicity ethambutol extrapulmonary tuberculosis testicular tuberculosis |
url | http://www.ijmyco.org/article.asp?issn=2212-5531;year=2020;volume=9;issue=3;spage=322;epage=324;aulast=Pereira |
work_keys_str_mv | AT flaviogodinhopereira isolatedtesticulartuberculosiswithethambutolcutaneoustoxicityacombinationoftworareentities AT marianadasilvaleal isolatedtesticulartuberculosiswithethambutolcutaneoustoxicityacombinationoftworareentities AT susanacavadas isolatedtesticulartuberculosiswithethambutolcutaneoustoxicityacombinationoftworareentities AT inesladeira isolatedtesticulartuberculosiswithethambutolcutaneoustoxicityacombinationoftworareentities |