PPARα and PPARβ/δ are negatively correlated with proinflammatory markers in leukocytes of an obese pediatric population

PPARα and PPARβ/δ are negatively correlated with proinflammatory markers in leukocytes of an obese pediatric population

Abstract Background Obesity configures a pathophysiological profile that predisposes the development of metabolic and cardiovascular diseases, critically impacting public health. The chronic dysregulation of immuno-metabolic components triggered by pediatric obesity is a common but scarcely understo...

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Bibliographic Details
Main Authors: Karina Vargas-Sánchez, Laura Vargas, Yenny Urrutia, Iván Beltrán, Ana Beatriz Rossi, Hernán Yupanqui Lozano, Jorge Guarín, Monica Losada-Barragán
Format: Article
Language:English
Published: BMC 2020-10-01
Series:Journal of Inflammation
Subjects:
Obesity
Children
Adolescents
PPAR
GLP-1R
Cytokines
Online Access:http://link.springer.com/article/10.1186/s12950-020-00264-2

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