Nanozymes: Versatile Platforms for Cancer Diagnosis and Therapy
Abstract Natural enzymes usually suffer from high production cost, ease of denaturation and inactivation, and low yield, making them difficult to be broadly applicable. As an emerging type of artificial enzyme, nanozymes that combine the characteristics of nanomaterials and enzymes are promising alt...
| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
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SpringerOpen
2022-04-01
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| Series: | Nano-Micro Letters |
| Subjects: | |
| Online Access: | https://doi.org/10.1007/s40820-022-00828-2 |
| _version_ | 1818066730606395392 |
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| author | Xiaodong Zhang Xiaokai Chen Yanli Zhao |
| author_facet | Xiaodong Zhang Xiaokai Chen Yanli Zhao |
| author_sort | Xiaodong Zhang |
| collection | DOAJ |
| description | Abstract Natural enzymes usually suffer from high production cost, ease of denaturation and inactivation, and low yield, making them difficult to be broadly applicable. As an emerging type of artificial enzyme, nanozymes that combine the characteristics of nanomaterials and enzymes are promising alternatives. On the one hand, nanozymes have high enzyme-like catalytic activities to regulate biochemical reactions. On the other hand, nanozymes also inherit the properties of nanomaterials, which can ameliorate the shortcomings of natural enzymes and serve as versatile platforms for diverse applications. In this review, various nanozymes that mimic the catalytic activity of different enzymes are introduced. The achievements of nanozymes in different cancer diagnosis and treatment technologies are summarized by highlighting the advantages of nanozymes in these applications. Finally, future research directions in this rapidly developing field are outlooked. |
| first_indexed | 2024-12-10T15:12:26Z |
| format | Article |
| id | doaj.art-7ffdb1dc734246e5b5e1c736802a8a7d |
| institution | Directory Open Access Journal |
| issn | 2311-6706 2150-5551 |
| language | English |
| last_indexed | 2024-12-10T15:12:26Z |
| publishDate | 2022-04-01 |
| publisher | SpringerOpen |
| record_format | Article |
| series | Nano-Micro Letters |
| spelling | doaj.art-7ffdb1dc734246e5b5e1c736802a8a7d2022-12-22T01:43:53ZengSpringerOpenNano-Micro Letters2311-67062150-55512022-04-0114112710.1007/s40820-022-00828-2Nanozymes: Versatile Platforms for Cancer Diagnosis and TherapyXiaodong Zhang0Xiaokai Chen1Yanli Zhao2Division of Chemistry and Biological Chemistry, School of Physical and Mathematical Sciences, Nanyang Technological UniversityDivision of Chemistry and Biological Chemistry, School of Physical and Mathematical Sciences, Nanyang Technological UniversityDivision of Chemistry and Biological Chemistry, School of Physical and Mathematical Sciences, Nanyang Technological UniversityAbstract Natural enzymes usually suffer from high production cost, ease of denaturation and inactivation, and low yield, making them difficult to be broadly applicable. As an emerging type of artificial enzyme, nanozymes that combine the characteristics of nanomaterials and enzymes are promising alternatives. On the one hand, nanozymes have high enzyme-like catalytic activities to regulate biochemical reactions. On the other hand, nanozymes also inherit the properties of nanomaterials, which can ameliorate the shortcomings of natural enzymes and serve as versatile platforms for diverse applications. In this review, various nanozymes that mimic the catalytic activity of different enzymes are introduced. The achievements of nanozymes in different cancer diagnosis and treatment technologies are summarized by highlighting the advantages of nanozymes in these applications. Finally, future research directions in this rapidly developing field are outlooked.https://doi.org/10.1007/s40820-022-00828-2Cancer theranosticsCatalytic therapyEnzyme mimicsNanozymesSmart nanomedicine |
| spellingShingle | Xiaodong Zhang Xiaokai Chen Yanli Zhao Nanozymes: Versatile Platforms for Cancer Diagnosis and Therapy Nano-Micro Letters Cancer theranostics Catalytic therapy Enzyme mimics Nanozymes Smart nanomedicine |
| title | Nanozymes: Versatile Platforms for Cancer Diagnosis and Therapy |
| title_full | Nanozymes: Versatile Platforms for Cancer Diagnosis and Therapy |
| title_fullStr | Nanozymes: Versatile Platforms for Cancer Diagnosis and Therapy |
| title_full_unstemmed | Nanozymes: Versatile Platforms for Cancer Diagnosis and Therapy |
| title_short | Nanozymes: Versatile Platforms for Cancer Diagnosis and Therapy |
| title_sort | nanozymes versatile platforms for cancer diagnosis and therapy |
| topic | Cancer theranostics Catalytic therapy Enzyme mimics Nanozymes Smart nanomedicine |
| url | https://doi.org/10.1007/s40820-022-00828-2 |
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