A Hospital Based Serosurveillance Study of Dengue Infection in Jaipur (Rajasthan) , India
Background: Dengue has been known to be endemic in India for over two centuries. There is a need to assess the magnitude of dengue virus establishment in the state of Rajasthan. A surveillance study was conducted to analyze dengue seropositivity among patients with clinical suspicion of dengue f...
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| Format: | Article |
| Language: | English |
| Published: |
JCDR Research and Publications Private Limited
2013-09-01
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| Series: | Journal of Clinical and Diagnostic Research |
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| Online Access: | https://jcdr.net/articles/PDF/3357/24-%205562_PF1(M)_E(C)_F(T)_PF1(V)_PF1(T)_PFA(P)1.pdf |
| Summary: | Background: Dengue has been known to be endemic in India for
over two centuries. There is a need to assess the magnitude of
dengue virus establishment in the state of Rajasthan. A surveillance
study was conducted to analyze dengue seropositivity among
patients with clinical suspicion of dengue fever like illness, who
presented to or were admitted at a tertiary care private hospital
at Jaipur.
Methods: Serum samples from 2169 suspected dengue cases
(1356 males and 813 females) were received in the Serology
lab over the four year study period (2008-2011). The samples
were subjected to a rapid immuno-chromatography assay with
differential detection of IgM and IgG antibodies. A primary dengue
infection was defined by a positive IgM band and a negative IgG
band, whereas a secondary infection was defined by a positive Ig
G band with or without an IgM band.
Result: Among the 2169 patients who were screened; 18.99%
(412) were dengue specific IgM positive cases. 64. 49% (1399)
cases were negative for dengue specific antibodies, 5.67%
(123) were primary dengue cases, and 23.51% (510) were total
secondary dengue cases. During the study period, the Dengue
IgM seropositivity was highest in the year 2009 and was lowest
in the year 2011. Most of the cases occurred in the post-monsoon
season, with a peak in the month of October, each year.
Conclusion: A detailed and continuous epidemiological surveillance is required, for monitoring the incrusion and spread of
dengue viruses. This will help in undertaking and implementing
effective control and management strategies. |
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| ISSN: | 2249-782X 0973-709X |